Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment
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DOI: 10.1002/1878-0261.13322
Abstract: We previously observed increased levels of adenosine‐deaminase‐acting‐on‐dsRNA (Adar)‐dependent RNA editing during mesothelioma development in mice exposed to asbestos. The aim of this study was to characterize and assess the role of ADAR‐dependent RNA editing in… read more here.
Keywords: rna editing; adar2; rna; mesothelioma ... See more keywords
The RNA editing enzyme ADAR2 restricts L1 mobility.
Sign Up to like & getrecommendations! Published in 2021 at "RNA biology"
DOI: 10.1080/15476286.2021.1940020
Abstract: Adenosine deaminases acting on RNA (ADARs) are enzymes that convert adenosines to inosines in double-stranded RNAs (RNA editing A-to-I). ADAR1 and ADAR2 were previously reported as HIV-1 proviral factors. The aim of this study was… read more here.
Keywords: adar2 restricts; adar2; rna editing; enzyme adar2 ... See more keywords
Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development
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DOI: 10.1242/jcs.200055
Abstract: ABSTRACT Adenosine to inosine (A-to-I) RNA editing is important for a functional brain, and most known sites that are subject to selective RNA editing have been found to result in diversified protein isoforms that are… read more here.
Keywords: adenosine inosine; rna; adar2; inosine rna ... See more keywords
A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing.
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DOI: 10.1261/rna.072728.119
Abstract: Adenosine-to-inosine RNA editing is an essential posttranscriptional modification catalyzed by adenosine deaminase acting on RNA (ADAR)1 and ADAR2 in mammals. For numerous sites in coding sequences (CDS) and microRNAs, editing is highly conserved and has… read more here.
Keywords: adar1 adar2; rna; adar2; site ... See more keywords