Abstract 5658: A homogenous PBMC ADCC bioassay enables bridging studies with ADCC reporter bioassays in immunotherapy monoclonal antibody development
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DOI: 10.1158/1538-7445.am2020-5658
Abstract: Measurement of antibody-dependent cellular cytotoxicity (ADCC) is critical for characterizing antibody Fc effector functions during monoclonal antibody development. Classic ADCC assays measure the short-term cytotoxicity of target cells, typically pre-loaded with radioactive or fluorescent dyes,… read more here.
Keywords: antibody development; adcc reporter; antibody; monoclonal antibody ... See more keywords