On‐treatment changes of serum Wisteria floribunda agglutinin‐positive Mac‐2 binding protein are associated with the regression of liver fibrosis in chronic hepatitis B patients on interferon α add‐on therapy
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DOI: 10.1002/jmv.25465
Abstract: Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein (M2BP) has been identified as a predictor for the response of interferon α (IFN‐α) in patients with viral hepatitis. However, whether serum glycosylation isomer of M2BP (M2BPGi) was associated with… read more here.
Keywords: fibrosis; add therapy; regression; hepatitis ... See more keywords
Dutasteride add‐on therapy reduces detrusor mass in patients with benign prostatic enlargement not satisfied with alpha‐adrenergic antagonist monotherapy: A single center prospective study
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DOI: 10.1002/nau.23247
Abstract: The ultrasound assessment of bladder wall thickness (BWT) and intravesical prostatic protrusion (IPP) have emerged as a non‐invasive, inexpensive, time‐saving alternatives to pressure‐flow studies to assess benign prostatic obstruction (BPO). Aim of our study was… read more here.
Keywords: add therapy; benign prostatic; prostatic enlargement; detrusor mass ... See more keywords
Efficacy of NB-UVB as Add-on Therapy to Antihistamine in the Treatment of Chronic Urticaria: A Systematic Review and Meta-analysis
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DOI: 10.1007/s13555-021-00510-2
Abstract: Narrow-band ultraviolet B (NB-UVB) phototherapy has been used for the treatment of chronic urticaria (CU), but the clinical efficacy of this treatment modality requires further evidence. A systematic review and meta-analysis of randomized clinical trials… read more here.
Keywords: add therapy; treatment; efficacy; uvb add ... See more keywords
Comparison of Silodosin Monotherapy vs Silodosin With Tadalafil Add-on Therapy in Patients With Benign Prostatic Hyperplasia.
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DOI: 10.1016/j.urology.2017.04.012
Abstract: OBJECTIVE To evaluate the efficacy and safety of add-on therapy with the phosphodiesterase type 5 inhibitor tadalafil for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH) treated with the α1-adrenoceptor blocker… read more here.
Keywords: add therapy; benign prostatic; tadalafil; silodosin ... See more keywords
Mirabegron versus Placebo Add-on Therapy in Men with Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: a Safety Analysis from the Randomized, Phase 4 PLUS Study.
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DOI: 10.1016/j.urology.2020.09.040
Abstract: OBJECTIVES To analyze the safety of mirabegron add-on therapy in men with overactive bladder symptoms concurrently receiving tamsulosin for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). METHODS The Phase 4 PLUS… read more here.
Keywords: add therapy; safety; mirabegron; teaes ... See more keywords
Effect of tolvaptan on long-term prognosis in Japanese patients with heart failure: a systematic review and meta-analysis
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DOI: 10.1093/ehjci/ehaa946.1027
Abstract: Tolvaptan (TLV), a vasopressin antagonist, can promote water diuresis and overcome various disadvantages associated with conventional diuretics by ameliorating congestive symptoms and improving hyponatremia while maintaining haemodynamics and renal function. Large-scale clinical trials conducted primarily… read more here.
Keywords: add therapy; long term; prognosis; tlv add ... See more keywords
Efficacy and safety of lixisenatide as add‐on therapy to basal insulin in older adults with type 2 diabetes in the GetGoal‐O Study
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DOI: 10.1111/1753-0407.12952
Abstract: This study compared the efficacy and safety of lixisenatide with placebo as add‐on therapy to basal insulin (BI) in adults aged ≥70 years with type 2 diabetes (T2D), with or without moderate renal insufficiency. read more here.
Keywords: therapy basal; add therapy; safety lixisenatide; efficacy safety ... See more keywords
Efficacy and safety of two dosages of canrenone as add‐on therapy in hypertensive patients taking ace‐inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE‐IT trial
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DOI: 10.1111/1755-5922.12235
Abstract: Summary Aim To evaluate the effects of canrenone as add‐on therapy in patients already treated with angiotensin‐converting enzyme inhibitors (ACE‐I) or angiotensin II receptor blockers (ARBs) and hydrochlorothiazide at the maximum dosage (25 mg/d). Method… read more here.
Keywords: canrenone; trial; canrenone add; add therapy ... See more keywords
Dual add‐on therapy of gemigliptin and dapagliflozin in patients with type 2 diabetes inadequately controlled with metformin alone: The SOLUTION 2 study
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DOI: 10.1111/dom.15717
Abstract: To evaluate the efficacy and safety of gemigliptin and dapagliflozin dual add‐on therapy (GEMI + DAPA) to metformin in type 2 diabetes (T2D) patients who had inadequate glycaemic control on metformin alone, compared with a single add‐on… read more here.
Keywords: gemigliptin dapagliflozin; add; dual add; type diabetes ... See more keywords
Efficacy of Tokishakuyakusan add‐on therapy with low‐dose oral contraceptive pills on endometriosis patients with dysmenorrhea
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DOI: 10.1111/jog.14424
Abstract: Tokishakuyakusan (TSS) is representative of popular Kampo medicines for Japanese women to treat dysmenorrhea, irregular menstruation and menopause. Current hormonal treatments and low‐dose oral contraceptives (OCs) used as a first‐choice drug for primary symptoms, however,… read more here.
Keywords: low dose; add therapy; efficacy tokishakuyakusan; dose oral ... See more keywords
Sodium-glucose co-transporter-2 inhibitors in Type 1 Diabetes: A Scoping Review.
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DOI: 10.1159/000527653
Abstract: BACKGROUND With recent developments in diabetes technology, attaining adequate glucose control is more achievable than ever. Despite these improvements a significant proportion of individuals with type 1 diabetes (T1D) do not reach recommended glycaemic goals.… read more here.
Keywords: therapy insulin; add therapy; type diabetes; sglt2 inhibitors ... See more keywords