Biological Evidence for Paradoxical Improvement of Psychiatric Disorder Symptoms by Addictive Drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2017.03.005
Abstract: Addiction biology has focused on the mechanisms of the positive and negative reinforcing actions of addictive drugs but neglected potential benefits. Two new studies provide the first insights into a neurobiology of psychoactive drug instrumentalization.… read more here.
Keywords: evidence paradoxical; addictive drugs; paradoxical improvement; improvement psychiatric ... See more keywords
A Review of the Metabolism and Potential Drug-drug Interactions With Addictive Drugs
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Addiction Medicine"
DOI: 10.1097/adm.0000000000000824
Abstract: Supplemental Digital Content is available in the text People who use drugs (PWUD) are at increased risk for drug-related harms such as overdose. Additionally, they are also at increased risk of secondary harms from bacterial… read more here.
Keywords: metabolism potential; drug interactions; drug; review metabolism ... See more keywords
An Overview of Appetite-Regulatory Peptides in Addiction Processes; From Bench to Bed Side
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.774050
Abstract: There is a substantial need for new pharmacological treatments of addiction, and appetite-regulatory peptides are implied as possible candidates. Appetite regulation is complex and involves anorexigenic hormones such as glucagon-like peptide-1 (GLP-1) and amylin, and… read more here.
Keywords: regulatory peptides; addiction processes; overview appetite; addictive drugs ... See more keywords
Epigenetic Effects of Addictive Drugs in the Nucleus Accumbens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.828055
Abstract: Substance use induces long-lasting behavioral changes and drug craving. Increasing evidence suggests that epigenetic gene regulation contributes to the development and expression of these long-lasting behavioral alterations. Here we systematically review extensive evidence from rodent… read more here.
Keywords: addictive drugs; effects addictive; epigenetic effects; use ... See more keywords