DABCO-mediated aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to cycloalkenones. Regioselective synthesis of disubstituted 1,2,3-triazoles
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DOI: 10.1016/j.tetlet.2016.11.125
Abstract: Abstract Aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to 2-cycloalken-1-ones has been studied in the presence of DABCO as organic base. The reactions were carried out in acetonitrile at room temperature to provide 2,4-disubstituted 2H-1,2,3-triazoles as major adducts… read more here.
Keywords: disubstituted triazoles; aryl triazoles; michael addition; aza michael ... See more keywords
Oxidative Addition of Aryl Halides to a Ni(I)-Bipyridine Complex.
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DOI: 10.1021/jacs.2c00462
Abstract: The oxidative addition of aryl halides to bipyridine- or phenanthroline-ligated nickel(I) is a commonly proposed step in nickel catalysis. However, there is a scarcity of complexes of this type that both are well-defined and undergo… read more here.
Keywords: addition; addition aryl; oxidative addition; aryl halides ... See more keywords
Enantioselective transannular reactions by palladium-catalysed conjugate addition of aryl boronic acids.
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DOI: 10.1039/d2cc01642g
Abstract: A palladium-catalyzed asymmeric conjugate addition of aryl boronic acids to medium-sized cycloalkenones followed by intramolecular aldol trapping is reported. The use of in situ formed [Pd/(QuinoxP*)] as the catalyst enables the synthesis of arylbicyclic scaffolds… read more here.
Keywords: boronic acids; addition aryl; conjugate addition; aryl boronic ... See more keywords
Regiospecific Aza-Michael Addition of 4-Aryl-1H-1,2,3-triazoles to Chalcones: Synthesis of 2,4-Disubstituted 1,2,3-Triazoles in Basic Medium
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DOI: 10.1055/s-0036-1588567
Abstract: A novel metal-free and base-mediated method to display the donor ability of 1,2,3-triazoles for the synthesis of 2,4-disubstituted 1,2,3-triazoles has been developed. A DABCO-promoted aza-Michael addition of 4-aryl NH-1,2,3-triazoles to α,β-unsaturated ketones (chalcones) is presented.… read more here.
Keywords: disubstituted triazoles; addition; michael addition; synthesis disubstituted ... See more keywords
Synthesis and Antimicrobial Activity of the Pathogenic E. coli Strains of p-Quinols: Additive Effects of Copper-Catalyzed Addition of Aryl Boronic Acid to Benzoquinones
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DOI: 10.3390/ijms24021623
Abstract: A mild and efficient protocol for the synthesis of p-quinols under aqueous conditions was developed. The pivotal role of additives in the copper-catalyzed addition of aryl boronic and heteroaryl boronic acids to benzoquinones was observed.… read more here.
Keywords: antimicrobial activity; addition aryl; catalyzed addition; activity ... See more keywords