Zinc-mediated enantioselective addition of terminal 3-en-1-ynes to cyclic trifluoromethyl ketimines
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2018.01.008
Abstract: Abstract A facile enantioselective addition of terminal 3-en-1-ynes to cyclic N-acyl trifluoromethyl ketimines is reported. In the presence of Zinc/BINOL complexes, a series of enynylated tertiary carbinamines were readily obtained in 90–97% yield with 70–97%… read more here.
Keywords: enantioselective addition; ynes cyclic; trifluoromethyl ketimines; addition terminal ... See more keywords
Three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00374k
Abstract: This paper described the unprecedented three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite. This new type of addition proceeds smoothly to produce gem-dichloroalkane derivatives in satisfactory to excellent yields via successive two-time additions… read more here.
Keywords: addition; component addition; alkynes carboxylic; addition terminal ... See more keywords