Regioselectivity of the OH Radical Addition to Uracil in Nucleic Acids. A Theoretical Approach Based on QM/MM Simulations.
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DOI: 10.1021/acs.jctc.7b00610
Abstract: Oxidation of nucleic acids is ubiquitous in living beings under metabolic impairments and/or exposed to external agents such as radiation, pollutants, or drugs, playing a central role in the development of many diseases mediated by… read more here.
Keywords: addition; nucleic acids; addition uracil; regioselectivity ... See more keywords