Click-Addressable Cassette for Photoaffinity Labeling.
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DOI: 10.1021/acsmedchemlett.7b00516
Abstract: A small molecule 1 was designed to contain an alkyne, a trifluoromethyl phenyldiazirine, and a free piperidine-NH for facile conjugation to protein binding ligands. This "cassette" 1 was synthesized via a relatively direct route involving… read more here.
Keywords: addressable cassette; chemistry; photoaffinity; cassette photoaffinity ... See more keywords