Addressing Transcriptional Dysregulation in Cancer through CDK9 Inhibition
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DOI: 10.1021/acs.biochem.2c00609
Abstract: Undermining transcriptional addiction, the dependence of cancers on selected transcriptional programs, is critically important for addressing cancers with high unmet clinical need. Cyclin-dependent kinase 9 (CDK9) has long been considered an actionable therapeutic target for… read more here.
Keywords: cdk9; transcriptional dysregulation; addressing transcriptional; dysregulation cancer ... See more keywords