Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100542
Abstract: Chronic kidney disease is an increasingly serious public health problem worldwide. Our recent studies have shown that Huangjinsan has a renal protective effect on chronic kidney disease, but the specific mechanism by which this effect… read more here.
Keywords: kidney; chronic kidney; adenine induced; induced chronic ... See more keywords
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-020-01927-3
Abstract: The failure of autologous arteriovenous fistulas (AVFs) occurs primarily due to stenosis in the anastomotic site, which is mainly related to the development of neointimal hyperplasia (NIH). Therefore, we conducted a study to establish a… read more here.
Keywords: chronic kidney; adenine induced; aortocaval fistulas; induced chronic ... See more keywords
Effect of aqueous extract and anthocyanins of calyces of Hibiscus sabdariffa (Malvaceae) in rats with adenine‐induced chronic kidney disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.12748
Abstract: The aim of this work was to assess the possible beneficial effects of aqueous extracts of Hibiscus sabdariffa L. calyces and anthocyanins isolated therefrom in an adenine‐induced chronic kidney disease (CKD) model. read more here.
Keywords: chronic kidney; adenine induced; induced chronic; hibiscus sabdariffa ... See more keywords
Effects of Etanercept on TNF-α Inhibition in Rats with Adenine-Induced Chronic Kidney Disease
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DOI: 10.1155/2022/4970753
Abstract: Introduction Chronic kidney disease (CKD) constitutes a chronic inflammatory state associated with an increase in inflammatory mediators and profibrotic molecules such as tumor necrosis factor-α (TNF-α). Etanercept (ETA) is a TNF inhibitor widely used in… read more here.
Keywords: inhibition; adenine induced; tnf; chronic kidney ... See more keywords
The effect of swimming exercise on adenine-induced kidney disease in rats, and the influence of curcumin or lisinopril thereon
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0176316
Abstract: Patients with chronic kidney disease (CKD) have been reported to benefit from different types of exercises. It has also been shown that the ACE inhibitor lisinopril, and the natural product curcumin are also beneficial in… read more here.
Keywords: adenine induced; curcumin lisinopril; curcumin; kidney disease ... See more keywords
Upacicalcet, a positive allosteric modulator of the calcium-sensing receptor, prevents vascular calcification and bone disorder in a rat adenine-induced secondary hyperparathyroidism model.
Sign Up to like & getrecommendations! Published in 2022 at "Bone"
DOI: 10.2139/ssrn.4173884
Abstract: Secondary hyperparathyroidism (SHPT) is a major comorbidity of chronic kidney disease (CKD). Chronic elevation of PTH levels is associated with cortical bone deterioration and increase in the risk of fractures in CKD patients. Here, we… read more here.
Keywords: calcium; adenine induced; rat; bone ... See more keywords
The in vivo effects of adenine-induced chronic kidney disease on some renal and hepatic function and CYP450 metabolizing enzymes.
Sign Up to like & getrecommendations! Published in 2017 at "Physiological research"
DOI: 10.33549/physiolres.933374
Abstract: Adenine-induced model of chronic kidney disease (CKD) is a widely used model especially in studies testing novel nephroprotective agents. We investigated the effects of adenine-induced CKD in rats on the activities of some xenobiotic metabolizing… read more here.
Keywords: chronic kidney; adenine induced; metabolizing enzymes; effects adenine ... See more keywords
Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.603802
Abstract: It is well-known that all progressive chronic kidney disease (CKD) is pathologically characterized by tubulointerstitial fibrosis process. Multiple studies have shown the critical role of inflammation and fibrosis in the development of CKD. Hence strategies… read more here.
Keywords: signaling pathways; fibrosis; adenine induced; renal fibrosis ... See more keywords
Paradoxical reduction of plasma lipids and atherosclerosis in mice with adenine-induced chronic kidney disease and hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1088015
Abstract: Background Atherosclerotic cardiovascular disease is prevalent among patients with chronic kidney disease (CKD). In this study, we initially aimed to test whether vascular calcification associated with CKD can worsen atherosclerosis. However, a paradoxical finding emerged… read more here.
Keywords: adenine induced; disease; adenine; plasma ... See more keywords
Microbiome-Metabolomics Analysis Reveals the Protection Mechanism of α-Ketoacid on Adenine-Induced Chronic Kidney Disease in Rats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.657827
Abstract: Objectives: As nitrogen-free precursors of corresponding essential amino, α-ketoacid have been widely prescribed to end-stage renal disease patients together with a low protein diet However, the impact of α-ketoacid on intestinal microbiota in chronic kidney… read more here.
Keywords: adenine; kidney disease; adenine induced; chronic kidney ... See more keywords
Adenine-Induced Nephropathy Reduces Atherosclerosis in ApoE Knockout Mice
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081147
Abstract: Background: Cardiovascular events are the main cause of death in patients with chronic kidney disease. We hypothesize that the protective effects of renal cholesterol and vitamin D3 metabolism are lost under this condition. Nephropathy was… read more here.
Keywords: adenine induced; adenine; knockout mice; atherosclerosis ... See more keywords