Widespread adenine N6-methylation of active genes in fungi
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DOI: 10.1038/ng.3859
Abstract: N6-methyldeoxyadenine (6mA) is a noncanonical DNA base modification present at low levels in plant and animal genomes, but its prevalence and association with genome function in other eukaryotic lineages remains poorly understood. Here we report… read more here.
Keywords: adenine methylation; genes fungi; methylation active; widespread adenine ... See more keywords
Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abe7489
Abstract: The discovery of N6-methyldeoxyadenine (6mA) across eukaryotes led to a search for additional epigenetic mechanisms. However, some studies have highlighted confounding factors that challenge the prevalence of 6mA in eukaryotes. We developed a metagenomic method… read more here.
Keywords: dna; adenine methylation; deconvolution; 6ma eukaryotes ... See more keywords