Schistosoma mansoni displays an adenine phosphoribosyltransferase preferentially expressed in mature female gonads and vitelaria.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2017.04.004
Abstract: Schistosoma mansoni depends upon the purine salvage pathway to obtain purine nucleotides; therefore, enzymes from this pathway are essential for parasite survival. Here, we focused on the adenine phosphoribosyltransferase (APRT) enzyme, which catalyzes the condensation… read more here.
Keywords: mansoni; adenine phosphoribosyltransferase; displays adenine; schistosoma mansoni ... See more keywords
Guvermectin Biosynthesis Revealing the Key Role of a Phosphoribohydrolase and Structural Insight into the Active Glutamate of a Noncanonical Adenine Phosphoribosyltransferase.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00739
Abstract: Guvermectin is a novel plant growth regulator that has been registered as a new agrochemical in China. It is an adenosine analogue with an unusual psicofuranose instead of ribose. Herein, the gene cluster responsible for… read more here.
Keywords: guvermectin biosynthesis; biosynthesis; adenine phosphoribosyltransferase; guvermectin ... See more keywords
Robust Survival-Based RNA Interference of Gene Families Using in Tandem Silencing of Adenine Phosphoribosyltransferase.
Sign Up to like & getrecommendations! Published in 2020 at "Plant physiology"
DOI: 10.1104/pp.20.00865
Abstract: RNA interference (RNAi) enables flexible and dynamic interrogation of entire gene families or essential genes without the need for exogenous proteins, unlike CRISPR-Cas technology. Unfortunately, isolation of plants undergoing potent gene silencing requires laborious design,… read more here.
Keywords: gene families; adenine phosphoribosyltransferase; rna interference; rnai ... See more keywords