Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma
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DOI: 10.1001/jamaoncol.2017.3420
Abstract: Importance Although patients with resected pancreatic adenocarcinoma are at high risk for disease recurrence, few biomarkers are available to inform patient outcomes. Objective To evaluate the alterations of the 4 main driver genes in pancreatic… read more here.
Keywords: patients resected; driver genes; resected pancreatic; pancreatic adenocarcinoma ... See more keywords
Systematic exploration of the underlying mechanism of gemcitabine resistance in pancreatic adenocarcinoma
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DOI: 10.1002/1878-0261.13279
Abstract: Resistance to gemcitabine is the main challenge of chemotherapy for pancreatic ductal adenocarcinoma (PDAC). Hence, the development of a response signature to gemcitabine is essential for precision therapy of PDAC. However, existing quantitative signatures of… read more here.
Keywords: gps; resistance; gemcitabine; adenocarcinoma ... See more keywords
NICD3 regulates the expression of MUC5AC and MUC2 by recruiting SMARCA4 and is involved in the differentiation of mucinous colorectal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13296
Abstract: Adenocarcinoma is the most prevalent histological subtype of colorectal cancer (CRC), with mucinous colorectal adenocarcinoma (MCA) being a unique form. Although the mucinous subtype is known to elicit a worse response to chemotherapy and immunotherapy… read more here.
Keywords: colorectal adenocarcinoma; mucinous colorectal; crc; muc5ac muc2 ... See more keywords
Tumor immune microenvironment in therapy‐naive esophageal adenocarcinoma could predict the nodal status
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DOI: 10.1002/cam4.5386
Abstract: Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating… read more here.
Keywords: therapy naive; immune microenvironment; tumor immune; microenvironment therapy ... See more keywords
Evolution of lung adenocarcinoma from preneoplasia to invasive adenocarcinoma
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DOI: 10.1002/cam4.5393
Abstract: Mutations in driver genes contribute to the development and progression of lung adenocarcinoma (LUAD). However, in the dynamic evolutionary process from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and eventually to invasive adenocarcinoma… read more here.
Keywords: lung adenocarcinoma; invasive adenocarcinoma; evolution lung; preneoplasia ... See more keywords
Comparison of characteristics and outcomes of young‐onset versus average onset pancreatico‐biliary adenocarcinoma
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DOI: 10.1002/cam4.5418
Abstract: Young‐onset gastrointestinal malignancies appear to be increasing in incidence. There are limited data on young‐onset pancreaticobiliary adenocarcinoma (YO‐PBA). read more here.
Keywords: characteristics outcomes; onset versus; comparison characteristics; young onset ... See more keywords
Comparison of treatment strategies for resectable locally advanced primary mucinous adenocarcinoma of the lung
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DOI: 10.1002/cam4.5684
Abstract: Primary pure mucinous adenocarcinoma (PMA) is a rare type of lung cancer with unique clinical and prognostic features. Previous studies have shown that PMA have more early‐stage cancer compared with other adenocarcinoma (ADC) subtypes. The… read more here.
Keywords: locally advanced; treatment strategies; mucinous adenocarcinoma; adenocarcinoma ... See more keywords
Application of positron emission tomography imaging to personalize esophagogastric cancer care
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.31940
Abstract: The incidence and mortality of esophagogastric (EG) adenocarcinoma have been progressively increasing, particularly in Western countries. Genomically, these tumors are characterized by chromosomal instability, marked aneuploidy, and a high rate of TP53 mutations, contributing to… read more here.
Keywords: chemotherapy; pet; positron emission; cancer ... See more keywords
Updating the Papanicolaou Society cytologic criteria for invasive adenocarcinoma in cystic pancreaticobiliary specimens
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DOI: 10.1002/cncy.22487
Abstract: In contrast, the diagnosis of adenocarcinoma (which by definition is invasive because in situ lesions of the pancreas do not use the terminology of adenocarcinoma in situ) is based solely on cytologic criteria. However, when… read more here.
Keywords: invasive adenocarcinoma; criteria invasive; papanicolaou society; cytologic criteria ... See more keywords
Biliary cytology: A diagnostic tree for adenocarcinoma based on a cohort of 135 patients with endoscopic retrograde cholangiopancreatography for stenosis of the extrahepatic bile duct
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DOI: 10.1002/cncy.22565
Abstract: The diagnosis of well‐differentiated adenocarcinoma on bile aspiration is a well‐known challenge. This study was aimed at improving the diagnostic performance and providing a biliary cytology learning atlas. read more here.
Keywords: diagnostic tree; cytology diagnostic; biliary cytology; cytology ... See more keywords
Oncocytic poorly differentiated (insular) thyroid carcinoma mimicking metastatic adenocarcinoma. A case report and review of the literature
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DOI: 10.1002/dc.24147
Abstract: We report the cytohistologic and immunohistochemical findings of an oncocytic variant of poorly differentiated thyroid carcinoma in a 76‐year old man with a prior history of prostatic adenocarcinoma. The man complained of a palpable nodule… read more here.
Keywords: cytology; thyroid carcinoma; poorly differentiated; adenocarcinoma ... See more keywords