Potential and promising anticancer drugs from adenosine and its analogs.
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DOI: 10.1016/j.drudis.2021.02.020
Abstract: In recent years, many studies have shown that adenosine has efficacy for treating cancer. More importantly, some adenosine analogs have been successfully marketed to fulfill anticancer purposes. In this review, we summarize the anticancer effects… read more here.
Keywords: potential promising; drugs adenosine; anticancer drugs; adenosine analogs ... See more keywords
Facile synthesis of photoactivatable adenosine analogs
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DOI: 10.1039/d1ra08794k
Abstract: Adenosine and its derivatives are important building blocks of the biological system. They serve as the universal energy currency, amplify intracellular signals for various signal transduction pathways, and can also be used as the co-substrates… read more here.
Keywords: photoactivatable adenosine; facile synthesis; synthesis photoactivatable; synthesis ... See more keywords
Comparative analysis of stimulation and binding characteristics of adenosine analogs to AMP-activated protein kinase
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DOI: 10.1080/10286020.2018.1484454
Abstract: Abstract To compare the stimulation and binding characteristics of adenosine analogs including AMP, IMM-H007, and M1, to AMPK, and to explore the potential mechanism underlying the regulation effect of adenosine analogs on AMPK activity, [γ-32P]ATP… read more here.
Keywords: comparative analysis; binding characteristics; stimulation binding; characteristics adenosine ... See more keywords