Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase
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DOI: 10.1021/jacs.2c04808
Abstract: Prodrugs have little or no pharmacological activity and are converted to active drugs in the body by enzymes, metabolic reactions, or through human-controlled actions. However, prodrugs promoting their chemical bioconversion without any of these processes… read more here.
Keywords: trna synthetase; adenosine dependent; activation mechanism; dependent activation ... See more keywords