Abstract B05: Adenosine generation limits the ability of radiation therapy to induce antitumor immunity by abrogating recruitment and activation of CD103+ DCs
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DOI: 10.1158/2326-6074.tumimm17-b05
Abstract: Localized radiation therapy (RT) can act as a powerful adjuvant to immunotherapeutic strategies by triggering anti-tumor immune responses to poorly immunogenic tumors. Radiation of tumor cells induces a dose-dependent release of ATP, a molecule that… read more here.
Keywords: cd103 dcs; adenosine generation; dcs; activation ... See more keywords