Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00986-7
Abstract: The molecular mechanisms underlying vascular inflammation and associated inflammatory vascular diseases are not well defined. Here we show that endothelial intracellular adenosine and its key regulator adenosine kinase (ADK) play important roles in vascular inflammation.… read more here.
Keywords: adenosine kinase; vascular inflammation; inflammation; intracellular adenosine ... See more keywords
Erratum. Genetic Disruption of Adenosine Kinase in Mouse Pancreatic β-Cells Protects Against High-Fat Diet–Induced Glucose Intolerance. Diabetes 2017;66:1928–1938
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DOI: 10.2337/db17-er12f
Abstract: In the article listed above, Yassan Abdolazimi’s name was inadvertently misspelled in the … read more here.
Keywords: mouse pancreatic; adenosine kinase; genetic disruption; kinase mouse ... See more keywords
Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer
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DOI: 10.3390/biom12030418
Abstract: The immunosuppressive effect of adenosine in the microenvironment of a tumor is well established. Presently, researchers are developing approaches in immune therapy that target inhibition of adenosine or its signaling such as CD39 or CD73… read more here.
Keywords: adenosine kinase; adenosine; adenosine deaminase; enzymes adenosine ... See more keywords
A Novel Adenosine Kinase from Bombyx mori: Enzymatic Activity, Structure, and Biological Function
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DOI: 10.3390/ijms20153732
Abstract: Adenosine kinase (ADK) is the first enzyme in the adenosine remediation pathway that catalyzes adenosine phosphorylation into adenosine monophosphate, thus regulating adenosine homeostasis in cells. To obtain new insights into ADK from Bombyx mori (BmADK),… read more here.
Keywords: bombyx mori; adenosine kinase; activity structure; bmadk ... See more keywords