Presence of Coronary Endothelial Dysfunction, Coronary Vasospasm, and Adenosine-Mediated Vasodilatory Disorders in Patients With Ischemia and Nonobstructive Coronary Arteries
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DOI: 10.1161/circinterventions.122.012017
Abstract: Background: Coronary function testing in patients with ischemia and nonobstructive coronary arteries (INOCA) commonly includes assessment of adenosine-mediated vasodilation and acetylcholine spasm provocation. The purpose of this study was to evaluate the diagnostic value of… read more here.
Keywords: mediated vasodilation; dysfunction; endothelial dysfunction; adenosine mediated ... See more keywords
IL-4 prevents adenosine-mediated immunoregulation by inhibiting CD39 expression
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DOI: 10.1172/jci.insight.157509
Abstract: The ectonucleotidase CD39 functions as a checkpoint in purinergic signaling on effector T cells. By depleting eATP and initiating the generation of adenosine, it impairs memory cell development and contributes to T cell exhaustion, thereby… read more here.
Keywords: cell; adenosine mediated; expression; prevents adenosine ... See more keywords