Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2017.1370584
Abstract: Abstract Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse… read more here.
Keywords: homocysteine; human adenosyl; adenosyl homocysteine; homocysteine hydrolase ... See more keywords
S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
Sign Up to like & getrecommendations! Published in 2022 at "Aging cell"
DOI: 10.1111/acel.13604
Abstract: Methionine restriction (MetR) can extend lifespan and delay the onset of aging-associated pathologies in most model organisms. Previously, we showed that supplementation with the metabolite S-adenosyl-L-homocysteine (SAH) extends lifespan and activates the energy sensor AMP-activated… read more here.
Keywords: lifespan methionine; adenosyl homocysteine; extends lifespan; homocysteine extends ... See more keywords
S-Adenosyl-l-Homocysteine Exhibits Potential Antiviral Activity Against Dengue Virus Serotype-3 (DENV-3) in Bangladesh: A Viroinformatics-Based Approach
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322231158249
Abstract: Dengue outbreak is one of the concerning issues in Bangladesh due to the annual outbreak with the alarming number of death and infection. However, there is no effective antiviral drug available to treat dengue-infected patients.… read more here.
Keywords: serotype; adenosyl homocysteine; dengue virus; drug ... See more keywords