Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT)
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DOI: 10.1177/2472555219879644
Abstract: Nicotinamide mononucleotide adenylyltransferase (NMNAT; EC 2.7.7.1) catalyzes the reversible production of NAD+ from NMN+ and ATP and is a potential drug target for cancer and neurodegenerative diseases. A sensitive bioluminescent assay format suitable to high-throughput… read more here.
Keywords: nicotinamide mononucleotide; adenylyltransferase nmnat; throughput screening; bioluminescent ... See more keywords