Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development
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DOI: 10.1016/j.expneurol.2022.113994
Abstract: The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor. BAI1 is also a critical regulator of dendritic spine and excitatory synapse development… read more here.
Keywords: seizure susceptibility; adgrb1; mice; full length ... See more keywords