Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
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DOI: 10.1038/s41586-022-04580-w
Abstract: Adhesion G protein-coupled receptors (aGPCRs) are essential for a variety of physiological processes such as immune responses, organ development, cellular communication, proliferation and homeostasis1-7. An intrinsic manner of activation that involves a tethered agonist in… read more here.
Keywords: stalk; tethered agonism; adhesion; adgrd1 adgrf1 ... See more keywords