β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15332-7
Abstract: Rosettes are widely used in epithelial morphogenesis during embryonic development and organogenesis. However, their role in postnatal development and adult tissue maintenance remains largely unknown. Here, we show zona glomerulosa cells in the adult adrenal… read more here.
Keywords: rosette; zona glomerulosa; morphogenesis; catenin fgfr2 ... See more keywords
Critical roles of adherens junctions in diseases of the oral mucosa
Sign Up to like & getrecommendations! Published in 2022 at "Tissue Barriers"
DOI: 10.1080/21688370.2022.2084320
Abstract: ABSTRACT The oral cavity is directly exposed to a variety of environmental stimuli and contains a diverse microbiome that continuously interacts with the oral epithelium. Therefore, establishment and maintenance of the barrier function of the… read more here.
Keywords: roles adherens; critical roles; oral mucosa; junctions diseases ... See more keywords
The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjac037
Abstract: Abstract Fas-associated factor 1 (FAF1) is a scaffolding protein that plays multiple functions, and dysregulation of FAF1 is associated with many types of diseases such as cancers. FAF1 contains multiple ubiquitin-related domains (UBA, UBL1, UBL2,… read more here.
Keywords: rhoa activation; adherens junction; faf1; hsp70 ... See more keywords
Nectin1 expression is frequently decreased in gastric cancers
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DOI: 10.1111/pin.12721
Abstract: Gastric cancer (GC) is rich in many different histological types, but how the histological pattern is defined remains to be proved. The relation between GC histological types and the expression of nectin1, which is one… read more here.
Keywords: histological types; nectin1 expression; expression; adherens junction ... See more keywords
Abstract 215: Negative Regulation of Adherens Junction Formation Patterns Cellular Parameters Required for Cardiac Pacemaking
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/res.127.suppl_1.215
Abstract: Cardiac Pacemaker Cells (CPCs) rhythmically initiate the electrical impulses that drive heart contractions. Paradoxically, CPCs display the highest rate of spontaneous depolarization in the heart despite being subjected to unfavorable electrochemical conditions that should theoretically… read more here.
Keywords: heart; cpc; junction formation; adherens junction ... See more keywords
Comparative study of in vitro effects of different nanoparticles at non-cytotoxic concentration on the adherens junction of human vascular endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s208225
Abstract: Background Effects of different nanoparticles (NPs) exposure at acutely non-cytotoxic concentrations are particularly worthy to figure out, compare, and elucidate. Objective To investigate and compare the effect of a small library of NPs at non-cytotoxic… read more here.
Keywords: cytotoxic concentration; microscopy; chemistry; adherens junction ... See more keywords
Origin and Evolution of the Multifaceted Adherens Junction Component Plekha7
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.856975
Abstract: Plekha7 is a key adherens junction component involved in numerous functions in mammalian cells. Plekha7 is the most studied member of the PLEKHA protein family, which includes eight members with diverse functions. However, the evolutionary… read more here.
Keywords: gene; plekha7; junction component; adherens junction ... See more keywords
Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.998373
Abstract: The function and structure of the mammalian epithelial cell layer is maintained by distinct intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and desmosomes. The AJ is most integral for stabilizing cell-cell adhesion and… read more here.
Keywords: cell; junction proteins; proteins move; membrane ... See more keywords
Transcriptome analysis of adherens junction pathway-related genes after peripheral nerve injury
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.237127
Abstract: The neural regeneration process is driven by a wide range of molecules and pathways. Adherens junctions are critical cellular junctions for the integrity of peripheral nerves. However, few studies have systematically characterized the transcript changes… read more here.
Keywords: adherens junctions; junction pathway; adherens junction; nerve injury ... See more keywords