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   Articles with "adherent cell" as a keyword



Innovative fixed bed bioreactor platform: Enabling linearly scalable adherent cell biomanufacturing with real‐time biomass prediction from nutrient consumption

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recommendations! Published in 2024 at "Biotechnology Journal"

DOI: 10.1002/biot.202300635

Abstract: Scalable single‐use adherent cell‐based biomanufacturing platforms are essential for unlocking the full potential of cell and gene therapies. The primary objective of this study is to design and develop a novel fixed bed bioreactor platform… read more here.

Keywords: adherent cell; cell; bioreactor; bioreactor platform ... See more keywords

Simple, fast, cost‐efficient, reliable, and highly automated DNA content analysis of cells in adherent cultures

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recommendations! Published in 2024 at "Cytometry Part A"

DOI: 10.1002/cyto.a.24840

Abstract: The most commonly used flow cytometric (FCM) analysis of cellular DNA content relies on ethanol fixation followed by RNA digestion and propidium iodide (PI) intercalation into double‐stranded DNA. This is a laborious and time‐consuming procedure… read more here.

Keywords: dna content; adherent cell; analysis; dna ... See more keywords

Adherent cell remodeling on micropatterns is modulated by Piezo1 channels

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-84427-y

Abstract: Adherent cells utilize local environmental cues to make decisions on their growth and movement. We have previously shown that HEK293 cells grown on the fibronectin stripe patterns were elongated. Here we show that Piezo1 function… read more here.

Keywords: cell remodeling; remodeling micropatterns; piezo1; adherent cell ... See more keywords

Long-term adherent cell dynamics emerging from energetic and frictional interactions at the interface.

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recommendations! Published in 2023 at "Physical review. E"

DOI: 10.1103/physreve.107.034406

Abstract: Cell adhesion plays an important role in a wide range of biological situations, including embryonic development, cancer invasion, and wound healing. Although several computational models describing adhesion dynamics have been proposed, models applicable to long-term,… read more here.

Keywords: long term; cell; term adherent; adherent cell ... See more keywords