Host-bacteria interaction and adhesin study for development of therapeutics.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.151
Abstract: Host-pathogen interaction is one of the most important areas of study to understand the adhesion of the pathogen to the host organisms. To adhere on the host cell surface, bacteria assemble the diverse adhesive structures… read more here.
Keywords: bacterial adhesins; different bacterial; study; host ... See more keywords
Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori.
Sign Up to like & getrecommendations! Published in 2019 at "Protein expression and purification"
DOI: 10.1016/j.pep.2019.105446
Abstract: Helicobacter pylori is a pathogenic microorganism infecting approximately 50% of the global population, and establishes life-long colonization despite the hostile stomach environment. H. pylori employs a wide range of outer membrane proteins (adhesins) for epithelial… read more here.
Keywords: tag; laba; stability; adhesin ... See more keywords
The trimeric autotransporter adhesin BadA is required for in vitro biofilm formation by Bartonella henselae
Sign Up to like & getrecommendations! Published in 2019 at "NPJ Biofilms and Microbiomes"
DOI: 10.1038/s41522-019-0083-8
Abstract: Bartonellahenselae (Bh) is a Gram-negative rod transmitted to humans by a scratch from the common house cat. Infection of humans with Bh can result in a range of clinical diseases including lymphadenopathy observed in cat-scratch… read more here.
Keywords: bartonella; biofilm formation; biofilm; adhesin ... See more keywords
Molecular mechanism of extreme mechanostability in a pathogen adhesin
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aar2094
Abstract: How a pathogen holds on to its host Staphylococcus epidermidis and Staphylococcus aureus are pathogens that can form biofilms on implants and medical devices. Central to biofilm formation is a very tight interaction between microbial… read more here.
Keywords: pathogen; microscopy; force; spectroscopy ... See more keywords
Serotype-Specific Sugars Impact Structure but Not Functions of the Trimeric Autotransporter Adhesin EmaA of Aggregatibacter actinomycetemcomitans
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00215-22
Abstract: The human oral pathogen A. actinomycetemcomitans is a causative agent of periodontal and several systemic diseases. EmaA is a trimeric autotransporter protein adhesin important for colonization by this pathobiont in vivo. ABSTRACT The human oral… read more here.
Keywords: structure; aggregatibacter actinomycetemcomitans; trimeric autotransporter; adhesin emaa ... See more keywords
Escherichia coli Aggregates Mediated by Native or Synthetic Adhesins Exhibit Both Core and Adhesin-Specific Transcriptional Responses
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00690-23
Abstract: The formation of bacterial aggregates has an important role in both clinical and ecological contexts. Although these structures have been previously shown to be more resistant to stressful conditions, the genetic basis of this stress… read more here.
Keywords: aggregation; physiology; synthetic adhesins; adhesin ... See more keywords
A cryptic transcription factor regulates Caulobacter adhesin development
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010481
Abstract: Alphaproteobacteria commonly produce an adhesin that is anchored to the exterior of the envelope at one cell pole. In Caulobacter crescentus, this adhesin enables permanent attachment to solid surfaces and is known as the holdfast.… read more here.
Keywords: rtrc; transcription; development; transcription factor ... See more keywords
Adhesin related genes as potential markers for the enteroaggregative Escherichia coli category
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.997208
Abstract: Enteroaggregative Escherichia coli (EAEC) is an important cause of diarrhea in children and adults worldwide. This pathotype is phenotypically characterized by the aggregative-adherence (AA) pattern in HEp-2 cells and genetically associated to the presence of… read more here.
Keywords: enteroaggregative escherichia; presence; escherichia coli; adhesin ... See more keywords
New Insights into the Methylation of Mycobacterium tuberculosis Heparin Binding Hemagglutinin Adhesin Expressed in Rhodococcus erythropolis
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10091139
Abstract: In recent years, knowledge of the role that protein methylation is playing on the physiopathogenesis of bacteria has grown. In Mycobacterium tuberculosis, methylation of the heparin binding hemagglutinin adhesin modulates the immune response, making this… read more here.
Keywords: protein; methylation; heparin binding; adhesin ... See more keywords