Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.01.040
Abstract: Insulin secretion from pancreatic β cells is a highly complex and tightly regulated process. Its dysregulation is one characteristic of type 2 diabetes, and thus, an in-depth understanding of the mechanisms controlling insulin secretion is… read more here.
Keywords: insulin; involvement adhesion; insulin secretion; adhesion gpcrs ... See more keywords
Adhesion GPCRs in Kidney Development and Disease
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2018.00009
Abstract: Chronic kidney disease (CKD) represents the fastest growing pathology worldwide with a prevalence of >10% in many countries. In addition, kidney cancer represents 5% of all new diagnosed cancers. As currently no effective therapies exist… read more here.
Keywords: development disease; kidney development; disease; adhesion gpcrs ... See more keywords
Ligands and Beyond: Mechanosensitive Adhesion GPCRs
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15020219
Abstract: Cells respond to diverse types of mechanical stimuli using a wide range of plasma membrane-associated mechanosensitive receptors to convert extracellular mechanical cues into intracellular signaling. G protein-coupled receptors (GPCRs) represent the largest cell surface protein… read more here.
Keywords: beyond mechanosensitive; mechanosensitive adhesion; adhesion gpcrs; gpcrs ... See more keywords