Cardiomyocyte adhesion and hyperadhesion differentially require ERK1/2 and plakoglobin
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DOI: 10.1172/jci.insight.140066
Abstract: Arrhythmogenic cardiomyopathy (AC) is a heart disease often caused by mutations in genes coding for desmosomal proteins, including desmoglein-2 (DSG2), plakoglobin (PG), and desmoplakin (DP). Therapy is based on symptoms and limiting arrhythmia, because the… read more here.
Keywords: plakoglobin; adhesion hyperadhesion; cardiomyocyte adhesion; adhesion ... See more keywords