Articles with "adhesion molecule" as a keyword



Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation

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Published in 2017 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2017.0064

Abstract: Importance Accumulating evidence links inflammation and atrial fibrillation (AF). Objective To assess whether markers of systemic and atrial inflammation are associated with incident AF in the general population. Design, Setting, and Participants The Bruneck Study… read more here.

Keywords: atrial fibrillation; adhesion molecule; study; vascular cell ... See more keywords

Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells.

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Published in 2023 at "Advanced science"

DOI: 10.1002/advs.202204378

Abstract: Immune checkpoint inhibitor (ICI) clinically benefits cancer treatment. However, the ICI responses are only achieved in a subset of patients, and the underlying mechanisms of the limited response remain unclear. 160 patients with non-small cell… read more here.

Keywords: intracellular adhesion; checkpoint inhibitor; immune checkpoint; molecule ... See more keywords
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Choline ameliorates ethanol induced alterations in tyrosine phosphorylation and distribution in detergent-resistant membrane microdomains of L1 cell adhesion molecule in vivo.

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Published in 2020 at "Birth defects research"

DOI: 10.1002/bdr2.1657

Abstract: BACKGROUND Exposure to ethanol during pregnancy is the cause of fetal alcohol spectrum disorder. The function of L1 cell adhesion molecule (L1), critical for proper brain development, is dependent on detergent-resistant membrane microdomains (DRM). Ethanol… read more here.

Keywords: choline; cell adhesion; adhesion molecule; ethanol induced ... See more keywords

Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice

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Published in 2022 at "Brain and Behavior"

DOI: 10.1002/brb3.2558

Abstract: Intracerebral hemorrhage (ICH) is a subtype of stroke and results in neurological deficits in patients without any effective treatments. Artemisinin (ART), a well‐known antimalarial Chinese medicine, exerts multiple essential roles in the central and peripheral… read more here.

Keywords: cell adhesion; neurological deficits; adhesion molecule; intracerebral hemorrhage ... See more keywords

Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus

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Published in 2022 at "Developmental Dynamics"

DOI: 10.1002/dvdy.513

Abstract: The fasciculus retroflexus is the prominent efferent pathway from the habenular complex. Medial habenular axons form a core packet whereas lateral habenular axons course in a surrounding shell. Both groups of fibers share the same… read more here.

Keywords: fasciculation; adhesion molecule; fasciculus retroflexus;

Upstream transcription factor 1 suppresses laryngeal squamous cell carcinoma progression through transcriptional activation of junctional adhesion molecule 3

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Published in 2025 at "IUBMB Life"

DOI: 10.1002/iub.70013

Abstract: Laryngeal squamous cell carcinoma (LSCC) exhibits aggressive growth, frequent recurrence, and a notable resistance to existing treatments. Building upon prior discoveries that identified junctional adhesion molecule 3 (JAM3) as a critical tumor suppressor in LSCC,… read more here.

Keywords: squamous cell; adhesion molecule; cell carcinoma; laryngeal squamous ... See more keywords

Vascular cell adhesion molecule 1 in patients with severe osteoarthritis of the hip

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Published in 2019 at "Wiener Klinische Wochenschrift"

DOI: 10.1007/s00508-019-1497-2

Abstract: SummaryBackgroundOsteoarthritis (OA) of the hip is a frequent and debilitating joint disease. Only few clinical risk factors for hip OA are established and clinically applicable biomarkers to identify patients at risk are still lacking. The glycoprotein… read more here.

Keywords: patients severe; hip; cell adhesion; vascular cell ... See more keywords

Biomarkers Predicting Tissue Pharmacokinetics of Antimicrobials in Sepsis: A Review

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Published in 2022 at "Clinical Pharmacokinetics"

DOI: 10.1007/s40262-021-01102-1

Abstract: The pathophysiology of sepsis alters drug pharmacokinetics, resulting in inadequate drug exposure and target-site concentration. Suboptimal exposure leads to treatment failure and the development of antimicrobial resistance. Therefore, we seek to optimize antimicrobial therapy in… read more here.

Keywords: adhesion molecule; drug; tissue; physiology ... See more keywords

Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis

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Published in 2018 at "Brain, Behavior, and Immunity"

DOI: 10.1016/j.bbi.2018.06.014

Abstract: In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) autoaggressive CD4+ T cells cross the blood-brain barrier (BBB) and cause neuroinflammation. Therapeutic targeting of CD4+ T-cell trafficking into the CNS by blocking… read more here.

Keywords: jam; bbb; eae; adhesion molecule ... See more keywords

Biomarkers of Acute Graft-Versus-Host Disease: Surface Antigens and Micro Rnas in Extracellular Vesicles

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Published in 2019 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2018.12.223

Abstract: Introduction Biomarkers could be crucial to identify patients at high-risk of acute Graft-vs.-Host Disease (aGVHD). Given their involvement in inflammation, Extracellular Vesicles (EVs) may become attractive biomarkers. Moreover, EVs are non-invasively extracted from body fluids.… read more here.

Keywords: cell adhesion; host disease; surface antigens; adhesion molecule ... See more keywords

In silico designed RNA aptamer against epithelial cell adhesion molecule for cancer cell imaging.

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Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.01.028

Abstract: Aptamers are short, single-stranded oligonucleotides that bind to their targets with high affinity and specificity. Usually, aptamers are selected experimentally using SELEX approach. Here, we describe a computational approach for selection of aptamers for proteins,… read more here.

Keywords: epithelial cell; cell adhesion; rna aptamer; adhesion molecule ... See more keywords