Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24975
Abstract: Trastuzumab-emtansine (T-DM1) is an antibody-drug conjugate that specifically targets HER2 thanks to its antibody component trastuzumab. In spite of responses to this novel agent, acquired resistance to treatment remains a major obstacle. Prolonged in vitro… read more here.
Keywords: prostaglandin pathway; alterations cell; adhesion; cell adhesion ... See more keywords