Articles with "adipocyte" as a keyword



Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk

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Published in 2017 at "Obesity"

DOI: 10.1002/oby.21697

Abstract: To determine whether adipocyte diameters from three measurement methods are similarly associated with adiposity measurements and cardiometabolic variables. read more here.

Keywords: comparative analysis; adipocyte; three human; analysis three ... See more keywords

Impaired adrenergic agonist‐dependent beige adipocyte induction in aged mice

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Published in 2017 at "Obesity"

DOI: 10.1002/oby.21727

Abstract: There are two types of thermogenic adipocytes expressing uncoupling protein (UCP)−1: the brown adipocyte activated by adrenergic stimulation and the beige adipocyte that appears within the white adipose tissue (WAT) in response to chronic adrenergic… read more here.

Keywords: adrenergic agonist; adipocyte; adrenergic stimulation; impaired adrenergic ... See more keywords

Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance

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Published in 2018 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2018.04.022

Abstract: The adipose Nod-like receptor protein 3 (NLRP3) inflammasome senses danger-associated molecular patterns (DAMPs) and initiates insulin resistance, but the mechanisms of adipose inflammasome activation remains elusive. In this study, Homocysteine (Hcy) is revealed to be… read more here.

Keywords: hcy; adipocyte; nod like; resistance ... See more keywords

Probiotic Enterococcus faecalis AG5 mitigated high fat diet induced obesity and produced propionic acid stimulated apoptosis in 3T3-L1 pre-adipocyte.

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Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118292

Abstract: AIMS Probiotics and their metabolites (SCFA) can regulate energy homeostasis. The present study thus evaluates the synergistic effect of probiotic Enterococcus faecalis AG5 on HFD induced obesity and the role of propionic acid (PA) in… read more here.

Keywords: apoptosis; adipocyte; 3t3 pre; induced obesity ... See more keywords

Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep

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Published in 2020 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.110691

Abstract: Prenatal testosterone (T)-treated female sheep exhibit an enhanced inflammatory and oxidative stress state in the visceral adipose tissue (VAT) but not in the subcutaneous (SAT), while surprisingly maintaining insulin sensitivity in both depots. In adult… read more here.

Keywords: adipocyte; female sheep; depot specific; distribution ... See more keywords

Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells

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Published in 2020 at "Phytochemistry Letters"

DOI: 10.1016/j.phytol.2020.07.011

Abstract: Abstract Cynandione A (CA) is a major ingredient of Cynanchum wilfordii. Here, we report a new function of CA in adipogenesis in 3T3-L1 cells, a preadipocyte cell line. During adipogenic differentiation in 3T3-L1 cells, CA… read more here.

Keywords: adipocyte; adipocyte related; beige adipocyte; induces adipogenesis ... See more keywords

IL-1β promotes adipogenesis by directly targeting adipocyte precursors

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-51938-x

Abstract: Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage and show that adipocyte-specific deletion of IL-1 receptor… read more here.

Keywords: adipocyte; adipogenesis directly; postprandial surges; directly targeting ... See more keywords

Adipogenesis and metabolic health

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Published in 2019 at "Nature Reviews Molecular Cell Biology"

DOI: 10.1038/s41580-018-0093-z

Abstract: Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public health issue of major proportion. The expansion of adipose… read more here.

Keywords: adipogenesis metabolic; adipocyte; metabolic health; adipogenesis ... See more keywords

Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-17800-5

Abstract: Metastatic tumor cells engage the local tumor microenvironment and activate specific pro-survival mechanisms to thrive and progress in the harsh bone marrow niche. Here we show that the major contributors to the survival of carcinoma… read more here.

Keywords: tumor; adipocyte; bone; stress ... See more keywords

Car4-positive adipocyte progenitor cells adapt to the aging environment and work as protection against ROS via glutathione metabolism

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-17231-7

Abstract: The induction of beige adipocytes is significantly reduced in aged mice due to the senescence of adipocyte progenitor cells (APCs). Recent studies have revealed the existence of beige adipocyte subtypes, suggesting that APCs comprise a… read more here.

Keywords: adipocyte progenitor; adipocyte; car4 positive; aging environment ... See more keywords

A three-dimensional human adipocyte model of fatty acid-induced obesity

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Published in 2022 at "Biofabrication"

DOI: 10.1088/1758-5090/ac84b1

Abstract: Obesity prevalence has reached pandemic proportions, leaving individuals at high risk for the development of diseases such as cancer and type 2 diabetes. In obesity, to accommodate excess lipid storage, adipocytes become hypertrophic, which is… read more here.

Keywords: adipocyte; disease; acid; three dimensional ... See more keywords