Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk
Sign Up to like & getrecommendations! Published in 2017 at "Obesity"
DOI: 10.1002/oby.21697
Abstract: To determine whether adipocyte diameters from three measurement methods are similarly associated with adiposity measurements and cardiometabolic variables. read more here.
Keywords: comparative analysis; adipocyte; three human; analysis three ... See more keywords
Impaired adrenergic agonist‐dependent beige adipocyte induction in aged mice
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DOI: 10.1002/oby.21727
Abstract: There are two types of thermogenic adipocytes expressing uncoupling protein (UCP)−1: the brown adipocyte activated by adrenergic stimulation and the beige adipocyte that appears within the white adipose tissue (WAT) in response to chronic adrenergic… read more here.
Keywords: adrenergic agonist; adipocyte; adrenergic stimulation; impaired adrenergic ... See more keywords
Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.04.022
Abstract: The adipose Nod-like receptor protein 3 (NLRP3) inflammasome senses danger-associated molecular patterns (DAMPs) and initiates insulin resistance, but the mechanisms of adipose inflammasome activation remains elusive. In this study, Homocysteine (Hcy) is revealed to be… read more here.
Keywords: hcy; adipocyte; nod like; resistance ... See more keywords
Probiotic Enterococcus faecalis AG5 mitigated high fat diet induced obesity and produced propionic acid stimulated apoptosis in 3T3-L1 pre-adipocyte.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118292
Abstract: AIMS Probiotics and their metabolites (SCFA) can regulate energy homeostasis. The present study thus evaluates the synergistic effect of probiotic Enterococcus faecalis AG5 on HFD induced obesity and the role of propionic acid (PA) in… read more here.
Keywords: apoptosis; adipocyte; 3t3 pre; induced obesity ... See more keywords
Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110691
Abstract: Prenatal testosterone (T)-treated female sheep exhibit an enhanced inflammatory and oxidative stress state in the visceral adipose tissue (VAT) but not in the subcutaneous (SAT), while surprisingly maintaining insulin sensitivity in both depots. In adult… read more here.
Keywords: adipocyte; female sheep; depot specific; distribution ... See more keywords
Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2020.07.011
Abstract: Abstract Cynandione A (CA) is a major ingredient of Cynanchum wilfordii. Here, we report a new function of CA in adipogenesis in 3T3-L1 cells, a preadipocyte cell line. During adipogenic differentiation in 3T3-L1 cells, CA… read more here.
Keywords: adipocyte; adipocyte related; beige adipocyte; induces adipogenesis ... See more keywords
Adipogenesis and metabolic health
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-018-0093-z
Abstract: Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public health issue of major proportion. The expansion of adipose… read more here.
Keywords: adipogenesis metabolic; adipocyte; metabolic health; adipogenesis ... See more keywords
Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin
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DOI: 10.1038/s41598-017-17800-5
Abstract: Metastatic tumor cells engage the local tumor microenvironment and activate specific pro-survival mechanisms to thrive and progress in the harsh bone marrow niche. Here we show that the major contributors to the survival of carcinoma… read more here.
Keywords: tumor; adipocyte; bone; stress ... See more keywords
A three-dimensional human adipocyte model of fatty acid-induced obesity
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac84b1
Abstract: Obesity prevalence has reached pandemic proportions, leaving individuals at high risk for the development of diseases such as cancer and type 2 diabetes. In obesity, to accommodate excess lipid storage, adipocytes become hypertrophic, which is… read more here.
Keywords: adipocyte; disease; acid; three dimensional ... See more keywords
Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-000964
Abstract: The programmed death-ligand 1 (PD-L1)-dependent immune checkpoint attenuates host immunity and maintains self-tolerance. Imbalance between protective immunity and immunopathology due to altered PD-L1 signaling can lead to autoimmunity or tumor immunosuppression. The role of the… read more here.
Keywords: tumor; immunity; adipocyte; ablation ... See more keywords
Abstract 2560: Post-translational modification of focal adhesion kinase (FAK) protein increases in breast cancer cells upon exposure to conditioned medium derived from in vitro and in vivo adipocytes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2560
Abstract: Under obese conditions, dysregulation of the normal secretion of adipokines from fat cells has been shown to drive cancer progression. However, the role adipokine dysregulation plays in driving metastasis is still unclear. Recent studies have… read more here.
Keywords: adipocyte; vitro vivo; cancer; medium ... See more keywords