Adipose Morphology: a Critical Factor in Regulation of Human Metabolic Diseases and Adipose Tissue Dysfunction
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DOI: 10.1007/s11695-020-04983-6
Abstract: Emerging evidence highlights that dysfunction of adipose tissue contributes to impaired insulin sensitivity and systemic metabolic deterioration in obese state. Of note, adipocyte hypertrophy serves as a critical event which associates closely with adipose dysfunction.… read more here.
Keywords: dysfunction adipose; adipocyte hypertrophy; dysfunction; adipose tissue ... See more keywords
Adipocyte hypertrophy parallels alterations of mitochondrial status in a cell model for adipose tissue dysfunction in obesity.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118812
Abstract: AIMS Adipocyte hypertrophy is the main cause of obesity. A deeper understanding of the molecular mechanisms regulating adipocyte dysfunction may help to plan strategies to treat/prevent obesity and its metabolic complications. Here, we investigated in… read more here.
Keywords: dysfunction; adipocyte hypertrophy; model; hypertrophy ... See more keywords
Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo.
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DOI: 10.1016/j.nutres.2019.09.007
Abstract: Obesity-induced chronic inflammation in adipose tissue plays a critical role in the development of insulin resistance and various lifestyle-related diseases. Although gallic acid (GA) is known to exert protective effects on obesity-related complications, its function… read more here.
Keywords: gallic acid; adipocyte hypertrophy; interaction adipocytes; gene expression ... See more keywords
1866-P: Adipocyte Hypertrophy Is Associated with Increased Dietary Fatty Acid Storage in Adipose Tissue and Reduced Postprandial Hepatic Fatty Acid Uptake and Esterification in Humans
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DOI: 10.2337/db20-1866-p
Abstract: Introduction: Excessive exposure of lean tissues to nonesterified fatty acids (NEFA) leads to insulin resistance (IR). Adipocyte hypertrophy is associated with IR and increase in adipose tissue intracellular triglyceride lipolysis and in NEFA levels, that… read more here.
Keywords: none; adipocyte hypertrophy; tissue; postprandial hepatic ... See more keywords