METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia
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DOI: 10.1002/2211-5463.13165
Abstract: Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display enhanced adipogenesis compared with bone marrow MSCs from healthy donors. However, the precise… read more here.
Keywords: adipogenesis; chemoresistance acute; bone marrow; marrow mesenchymal ... See more keywords
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis
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DOI: 10.1002/advs.202100106
Abstract: Abstract Obesity and type 2 diabetes are strongly associated with adipose tissue dysfunction and impaired adipogenesis. Understanding the molecular underpinnings that control adipogenesis is thus of fundamental importance for the development of novel therapeutics against… read more here.
Keywords: organotypic microenvironment; improved adipogenesis; links organotypic; adipogenesis ... See more keywords
Insulin regulates Bbs4 during adipogenesis
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DOI: 10.1002/iub.1626
Abstract: Bardet‐Biedl syndrome (BBS) is a pleiotropic autosomal recessive disorder associated with marked obesity, increased susceptibility to insulin resistance and type 2 diabetes. However, it is unknown whether the link between BBS and diabetes is indirect… read more here.
Keywords: insulin; bbs4 adipogenesis; bbs; regulates bbs4 ... See more keywords
The skeletal cell‐derived molecule sclerostin drives bone marrow adipogenesis
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DOI: 10.1002/jcp.25976
Abstract: The bone marrow niche is a dynamic and complex microenvironment that can both regulate, and be regulated by the bone matrix. Within the bone marrow (BM), mesenchymal stromal cell (MSC) precursors reside in a multi‐potent… read more here.
Keywords: sclerostin; adipogenesis; bone; cell ... See more keywords
Cell shape alteration during adipogenesis is associated with coordinated matrix cues
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DOI: 10.1002/jcp.27157
Abstract: Obesity has become one of the leading pathophysiologic disorders in recent years. Adipose tissue is the main tissue related to obesity and is known to play a role in various physiological complications, including type 2… read more here.
Keywords: adipogenesis; cell shape; alteration adipogenesis; cell ... See more keywords
MicroRNA and Adipogenesis.
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DOI: 10.1007/978-3-319-48382-5_21
Abstract: In obesity, the process of adipogenesis largely determines the number of adipocytes in body fat depots. Adipogenesis is regulated by several adipocyte-selective microRNAs (miRNAs) and transcription factors that modulate adipocyte proliferation and differentiation. However, some… read more here.
Keywords: adipogenesis; microrna adipogenesis; biology;
Glucocorticoid Enhanced the Expression of Ski in Osteonecrosis of Femoral Head: The Effect on Adipogenesis of Rabbit BMSCs
Sign Up to like & getrecommendations! Published in 2019 at "Calcified Tissue International"
DOI: 10.1007/s00223-019-00592-3
Abstract: Glucocorticoid (GC)-induced osteonecrosis has been considered as the most serious side effect in long-term or over-dose steroid therapy. The decreased bone mass and increased marrow fat tissue demonstrated that GC can destroy the normal differentiation… read more here.
Keywords: osteonecrosis; expression ski; glucocorticoid; adipogenesis ... See more keywords
Tart cherry (Prunus cerasus L.) dietary supplement modulates visceral adipose tissue CB1 mRNA levels along with other adipogenesis-related genes in rat models of diet-induced obesity
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DOI: 10.1007/s00394-020-02459-y
Abstract: Purpose There is increasing evidence for the involvement of dietary bioactive compounds in the cross-talk modulation of endocannabinoid system and some of the key regulators of transcriptional control for adipogenesis. Methods We aimed to characterize… read more here.
Keywords: tart cherry; visceral adipose; adipogenesis; adipose tissue ... See more keywords
The suppressive effect of Gelidium amansi-EtOH extracts on the adipogenesis with MAPK signals in adipocytes with or without macrophages
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DOI: 10.1007/s10068-017-0230-z
Abstract: To elucidate the anti-inflammatory and anti-adipogenetic effects of Gelidium amansii (GA) ethanol extracts and their mechanisms, we performed two culture systems, adipocytes cultured with or without macrophages. Purified GA-3 fraction (GAE) contains high flavonoids and… read more here.
Keywords: gelidium; without macrophages; adipogenesis; gae ... See more keywords
Adipogenesis and lipid production in adipocytes subjected to sustained tensile deformations and elevated glucose concentration: a living cell-scale model system of diabesity
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DOI: 10.1007/s10237-017-1000-9
Abstract: Adipocyte fate commitment is characterized by morphological changes of fibroblastic pre-adipocyte cells, and specifically by accumulation of lipid droplets (LDs) as part of the adipogenesis metabolism. Formation of LDs indicates the production of triglycerides from… read more here.
Keywords: production; model system; adipogenesis; system diabesity ... See more keywords
Long non-coding RNA MEG3 inhibits adipogenesis and promotes osteogenesis of human adipose-derived mesenchymal stem cells via miR-140-5p
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DOI: 10.1007/s11010-017-3015-z
Abstract: AbstractlncRNAs are an emerging class of regulators involved in multiple biological processes. MEG3, an lncRNA, acts as a tumor suppressor, has been reported to be linked with osteogenic differentiation of MSCs. However, limited knowledge is… read more here.
Keywords: meg3; adipogenesis; differentiation; hascs ... See more keywords