Genetically modified mesenchymal stem/stromal cells transfected with adiponectin gene can stably secrete adiponectin
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.06.007
Abstract: Aims: Mesenchymal stem/stromal cells (MSCs) hold promises for the treatment of diverse diseases and regeneration of injured tissues. Genetic modification of MSCs through gene delivery might enhance their therapeutic potential. Adiponectin has been appeared as… read more here.
Keywords: adiponectin gene; stem stromal; adiponectin; mscs ... See more keywords
Adiponectin gene therapy prevents islet loss after transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17515
Abstract: Significant pancreatic islet dysfunction and loss shortly after transplantation to the liver limit the widespread implementation of this procedure in the clinic. Nonimmune factors such as reactive oxygen species and inflammation have been considered as… read more here.
Keywords: islet loss; transplantation; islet; adiponectin gene ... See more keywords
Associations between Adiponectin Gene Variability, Proinflammatory and Angiogenetic Markers: Implications for Microvascular Disease Development in Type 2 Diabetes Mellitus?
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DOI: 10.2174/1570161116666180108113825
Abstract: BACKGROUND Adiponectin gene (ADIPOQ) variability may affect the risk for type 2 diabetes mellitus (T2DM) but it remains unclear whether it is involved in microvascular complications. OBJECTIVE To explore the impact of ADIPOQ variability on… read more here.
Keywords: adiponectin gene; angiogenetic markers; variability; type diabetes ... See more keywords
Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients
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DOI: 10.3803/enm.2018.33.3.364
Abstract: Background Genetic variations in calpain-10 and adiponectin gene are known to influence insulin secretion and resistance in type 2 diabetes mellitus. Recently, several single nucleotide polymorphisms (SNPs) in calpain-10 and adiponectin gene have been reported… read more here.
Keywords: adiponectin gene; type diabetes; calpain adiponectin; diabetes patients ... See more keywords