Epistasis between ADIPOQ rs1501299 and PON1 rs662 polymorphisms is potentially associated with the development of knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04654-5
Abstract: Overweight produces oxidative stress (OS) on the articular cartilage, with the subsequent risk of developing knee osteoarthritis (OA). Associations between genetic polymorphisms related to OS and OA have been reported, but it is currently unknown… read more here.
Keywords: rs1501299; pon1; epistasis; knee ... See more keywords
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009019
Abstract: Loci identified in genome-wide association studies (GWAS) can include multiple distinct association signals. We sought to identify the molecular basis of multiple association signals for adiponectin, a hormone involved in glucose regulation secreted almost exclusively… read more here.
Keywords: loci; allelic heterogeneity; association; association signals ... See more keywords
Decreased long noncoding RNA ADIPOQ promoted cell proliferation and metastasis via miR-219c-3p/TP53 pathway in colorectal carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202007_22265
Abstract: OBJECTIVE To investigate the expression of Long non-coding RNA ADIPOQ and its facilitating effects on proliferation and invasion of colorectal cancer by modulating the expression of TP53 via sponging with miR-219c-3p. PATIENTS AND METHODS qRT-PCR… read more here.
Keywords: colorectal cancer; mir 219c; proliferation; expression ... See more keywords
Genetic variation in the ADIPOQ gene and serum adiponectin increase the risk of bladder cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied biomedicine"
DOI: 10.32725/jab.2022.012
Abstract: Bladder cancer (BC) is the 10th most common cancer worldwide. Genetic studies estimated 30% heritability in BC risk. Adiponectin is an adipocytokine that has important roles in the regulation of energy metabolism. Recent evidence suggests… read more here.
Keywords: adiponectin; adipoq; risk; serum adiponectin ... See more keywords
Dissecting the Molecular Role of ADIPOQ SNPs in Saudi Women Diagnosed with Gestational Diabetes Mellitus
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DOI: 10.3390/biomedicines11051289
Abstract: The traditional definition of gestational diabetes mellitus (GDM) is the leading cause of carbohydrate intolerance in hyperglycemia of varying severity, with onset or initial detection during pregnancy. Previous studies have reported a relationship among obesity,… read more here.
Keywords: adipoq; saudi arabia; molecular role; dissecting molecular ... See more keywords