Telmisartan attenuates diabetic nephropathy progression by inhibiting the dimerization of angiotensin type‐1 receptor and adiponectin receptor‐1
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.01.044
Abstract: Aims: The heterodimerization of angiotensin II receptors (AT1R and AT2R) with adiponectin receptor AdipoR1 and AdipoR2 may instigate high glucose (HG)‐induced renal tubulointerstitial injury. This study examined the effect of telmisartan on diabetic nephropathy (DN)… read more here.
Keywords: dimerization; telmisartan; adiponectin receptor; diabetic nephropathy ... See more keywords
Regulation of the cardioprotective adiponectin and its receptor AdipoR1 by salt.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0570
Abstract: Both circulating adiponectin (APN) and cardiac APN exert cardioprotective effects and improve insulin sensitivity and mitochondrial function. Low circulating APN serves as a biomarker for cardiovascular risk. Ablation of adiponectin receptor 1 (AdipoR1) causes myocardial… read more here.
Keywords: receptor adipor1; salt; apn; adiponectin receptor ... See more keywords
Adiponectin and adiponectin receptor 1 overexpression enhance inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-018-0419-3
Abstract: BackgroundAdiponectin (ADN) is an adipokine derived from adipocytes. It binds to adiponectin receptor 1 and 2 (AdipoR1 and R2) to exert its function in regulating whole-body energy homeostasis and inflammatory responses. However, the role of… read more here.
Keywords: adipor1 signaling; inflammatory bowel; inflammatory; adiponectin receptor ... See more keywords
Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192214995
Abstract: Adiponectin (ADIPOQ) as both a regulator of metabolic homeostasis and a protein involved in immune response might be of particular interest to contemporary laboratory medicine, especially in terms of minimally invasive diagnostics. The diverse roles… read more here.
Keywords: metabolic immune; adipor1; immune homeostasis; mrna levels ... See more keywords
miR-6835-3p regulates the function of pancreatic islet cells by modulating the expression of AdipoR1
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2018.3731
Abstract: Effective drugs and strategies for treating type 2 diabetes mellitus (2-DM) are urgently required. The aim of the present study was to elucidate the mechanism underlying microRNA (miR)-6835-3p regulation of adiponectin receptor 1 (AdipoR1) expression… read more here.
Keywords: insulin secretion; mir; expression; adipor1 ... See more keywords