Effect of Aerobic and Resistance Exercise on Cardiac Adipose Tissues: Secondary Analyses From a Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.2074
Abstract: Importance Epicardial and pericardial adipose tissues are emerging as important risk factors for cardiovascular disease, and there is a growing interest in discovering strategies to reduce the accumulation of fat in these depots. Objective To… read more here.
Keywords: mass; tissue mass; resistance; adipose tissue ... See more keywords
Adipocyte‐specific CDK7 ablation leads to progressive loss of adipose tissue and metabolic dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14335
Abstract: Adipose tissue regulates whole‐body energy homeostasis. Both lipodystrophy and obesity, the extreme and opposite aspects of adipose tissue dysfunction, result in metabolic disorders: insulin resistance and hepatic steatosis. Cyclin‐dependent kinases (CDKs) have been reported to… read more here.
Keywords: adipocyte specific; adipose tissue; dysfunction; specific cdk7 ... See more keywords
Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13782
Abstract: Obesity exacerbates the risk and aggressiveness of many types of cancer. Adipose tissue (AT) represents a prevalent component of the tumor microenvironment (TME) and contributes to cancer development and progression. Reciprocal communication between cancer and… read more here.
Keywords: tumor invasiveness; cancer; obesity; adam12 cyp1b1 ... See more keywords
The dipeptidyl peptidase‐4 (DPP‐4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12498
Abstract: To clarify the effects of a dipeptidyl peptidase‐4 (DPP‐4) inhibitor on whole‐body energy metabolism, we treated mice fed a high‐fat diet (HFD) with teneligliptin, a clinically available DPP‐4 inhibitor. Teneligliptin significantly prevented HFD‐induced obesity and… read more here.
Keywords: inhibitor; teneligliptin; obesity; dpp ... See more keywords
Differential expression of Ago2‐mediated microRNA signaling in adipose tissue is associated with food‐induced obesity
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13471
Abstract: Adipose tissue is a major component for the regulation of energy homeostasis by storage and release of lipids. As a core element of RNA‐induced silencing complex, argonaute2 (Ago2) plays critical role in maintenance of systemic… read more here.
Keywords: ago2; expression; adipose tissue; differential expression ... See more keywords
Determination of lower radiation dose limit for automatic measurement of adipose tissue
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13958
Abstract: Abstract The purpose of this study was to determine the lower limit of radiation dose required to measure visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) volumes when a fat quantification and noise reduction… read more here.
Keywords: dose limit; lower radiation; limit; adipose tissue ... See more keywords
A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202502711
Abstract: Systemic inflammation associated with obesity impairs skeletal muscle function through paracrine signaling from intermuscular adipose tissue-adipose depots situated between adjacent skeletal muscle groups-as well as from visceral adipose tissue, which consist of infiltrating macrophages surrounding… read more here.
Keywords: inflamed adipose; muscle; culture; muscle dysfunction ... See more keywords
Silicon‐Enhanced Adipogenesis and Angiogenesis for Vascularized Adipose Tissue Engineering
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201800776
Abstract: Abstract The enhancement of adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and sufficient vascularization remain great challenges for the successful reconstruction of engineered adipose tissue. Here, the bioactive effects of silicon (Si) ions… read more here.
Keywords: angiogenesis; adipogenic differentiation; tissue; adipose tissue ... See more keywords
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202100106
Abstract: Abstract Obesity and type 2 diabetes are strongly associated with adipose tissue dysfunction and impaired adipogenesis. Understanding the molecular underpinnings that control adipogenesis is thus of fundamental importance for the development of novel therapeutics against… read more here.
Keywords: organotypic microenvironment; improved adipogenesis; links organotypic; adipogenesis ... See more keywords
Fatty Liver/Adipose Tissue Dual‐Targeting Nanoparticles with Heme Oxygenase‐1 Inducer for Amelioration of Obesity, Obesity‐Induced Type 2 Diabetes, and Steatohepatitis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203286
Abstract: Persistent uptake of high‐calorie diets induces the storage of excessive lipid in visceral adipose tissue. Lipids secreted from obese adipose tissue are accumulated in peripheral tissues such as the liver, pancreas, and muscle, and impair… read more here.
Keywords: heme oxygenase; adipose tissue; type diabetes; pbp nps ... See more keywords
The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α‐ACER2‐Ceramide Signaling Axis
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202309525
Abstract: Metabolic abnormalities contribute to the pathogenesis of obesity and its complications. Yet, the understanding of the interactions between critical metabolic pathways that underlie obesity remains to be improved, in part owing to the lack of… read more here.
Keywords: hif2 acer2; obesity; acer2 ceramide; signaling axis ... See more keywords