Oroxylin A regulates the turnover of lipid droplet via downregulating adipose triglyceride lipase (ATGL) in hepatic stellate cells.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116934
Abstract: Proliferation and differentiation of hepatic stellate cells (HSCs) are the most noticeable events in hepatic fibrosis, in which the loss of lipid droplets (LDs) is the most important feature. However, the complex mechanisms of LD… read more here.
Keywords: adipose triglyceride; effect oroxylin; effect; hepatic stellate ... See more keywords
Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway
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DOI: 10.1111/jcmm.16349
Abstract: Abnormal lipid metabolism is the sign of tumour cells. Previous researches have revealed that the lipolytic pathway may contribute to the progression of colorectal cancer (CRC). However, adipose triglyceride lipase (ATGL) role in CRC cells… read more here.
Keywords: adipose triglyceride; crc cells; colorectal cancer; triglyceride lipase ... See more keywords
The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice
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DOI: 10.1186/s12944-019-1151-z
Abstract: The ability of mammals to store and draw on fat reserves has been a driving force throughout evolution in an environment with intermittent nutrient availability. The discovery of adipose triglyceride lipase (ATGL) as a triglyceride… read more here.
Keywords: adipose triglyceride; homeostasis; transgenic mice; atgl ... See more keywords
Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells
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DOI: 10.2337/db19-0951
Abstract: Lipid droplets (LDs) are frequently increased when excessive lipid accumulation leads to cellular dysfunction. Distinct from mouse β-cells, LDs are prominent in human β-cells. However, the regulation of LD mobilization (lipolysis) in human β-cells remains… read more here.
Keywords: adipose triglyceride; lipid droplets; lipase; mobilization ... See more keywords