Differential Protein Citrullination in Human ER– and ER+ Tumor and Adjacent Healthy Breast Tissue
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DOI: 10.1021/acs.biochem.2c00551
Abstract: Post-translational modification of arginine to citrulline is catalyzed by members of the peptidylarginine deiminase (PAD) family. Dysregulation of this catalysis is a significant driver of the pathogenesis of numerous inflammatory diseases, including cancer. However, dysregulation… read more here.
Keywords: citrullination; breast; tumor adjacent; adjacent healthy ... See more keywords