Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aba8853
Abstract: A PAMless base editor CRISPR-Cas DNA base editing typically requires a specific motif for targeting known as a protospacer-adjacent motif (PAM). This requirement limits the sequences within a genome that can be targeted. Walton et… read more here.
Keywords: near pamless; adjacent motif; crispr; protospacer adjacent ... See more keywords