Efficacy of adjunctive brexpiprazole on the core symptoms of major depressive disorder: A post hoc analysis of two pooled clinical studies.
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DOI: 10.1016/j.jad.2017.09.054
Abstract: BACKGROUND Patients with major depressive disorder (MDD) who do not adequately respond to antidepressant treatment (ADT) may benefit from adjunctive atypical antipsychotics; however, certain agents target specific symptoms of depression and not the full syndrome.… read more here.
Keywords: adjunctive brexpiprazole; post hoc; hoc analysis; core symptoms ... See more keywords
Patient-reported efficacy of adjunctive brexpiprazole in major depressive disorder in a phase 4, open-label, interventional study
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DOI: 10.1080/03007995.2025.2558140
Abstract: Abstract Objectives In ENGAGE, patients with major depressive disorder (MDD) demonstrated improvements in patient-reported depression and life engagement while taking adjunctive brexpiprazole. This analysis aimed to further characterize patient perspectives on the effects of adjunctive… read more here.
Keywords: pgi; word; adjunctive brexpiprazole; patient ... See more keywords
Effects of Adjunctive Brexpiprazole on Individual Depressive Symptoms and Functioning in Patients With Major Depressive Disorder and Anxious Distress
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DOI: 10.1097/jcp.0000000000001825
Abstract: Abstract Purpose/Background Anxiety symptoms in major depressive disorder (MDD) are frequent, and they decrease response to antidepressant treatment (ADT), and affect patient functioning. This post hoc analysis examined the efficacy of adjunctive brexpiprazole on individual… read more here.
Keywords: depressive symptoms; adjunctive brexpiprazole; anxious distress; functioning patients ... See more keywords
Effects of adjunctive brexpiprazole in patients with major depressive disorder and sleep disturbance: a post hoc analysis of three randomized trials
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2025.1618176
Abstract: Introduction Sleep disturbances are common in major depressive disorder (MDD). This post hoc analysis aimed to evaluate the effects of adjunctive brexpiprazole in patients with MDD and sleep disturbance. Methods Data were pooled from three… read more here.
Keywords: sleep disturbance; adjunctive brexpiprazole; disturbance; sdf ... See more keywords