Opicapone: once‐daily adjunctive therapy for Parkinson's disease
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DOI: 10.1002/psb.1543
Abstract: Opicapone (Ongentys) is a new once‐daily catechol‐O‐methyl transferase (COMT) inhibitor with a long duration of action allowing once‐daily dosing, licensed for adjunctive therapy in adults with Parkinson's disease and end‐of‐dose motor fluctuations. This article discusses… read more here.
Keywords: adjunctive therapy; opicapone daily; parkinson disease; therapy parkinson ... See more keywords
Melatonin as adjunctive therapy in patients admitted to the Covid-19
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DOI: 10.1016/j.amsu.2022.103492
Abstract: Objective Coronavirus has disrupted the natural order of the world since September 2019 with no specific medication. The beneficial effects of melatonin on sepsis and viral influenza were demonstrated previously, but its effects on covid-19,… read more here.
Keywords: patients admitted; melatonin adjunctive; covid icu; melatonin ... See more keywords
RENAL DENERVATION AS AN ADJUNCTIVE THERAPY TO CARDIAC SYMPATHETIC DENERVATION FOR ABLATION REFRACTORY VENTRICULAR TACHYCARDIA.
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DOI: 10.1016/j.hrthm.2019.09.016
Abstract: BACKGROUND Autonomic modulation is finding an increasing role in the treatment of ventricular arrhythmias. Renal denervation (RDN) has been described as a treatment modality for refractory ventricular tachycardia (VT) in case series. OBJECTIVE To evaluate… read more here.
Keywords: adjunctive therapy; denervation; ablation; csd ... See more keywords
Lurasidone and risk of metabolic syndrome: results from short and long-term studies in patients with bipolar depression.
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DOI: 10.1017/s1092852923001190
Abstract: OBJECTIVE The elevated prevalence of metabolic syndrome (MetS) in patients with depression has been associated with increased mortality. This post hoc analysis assessed the effect of treatment with lurasidone on risk of MetS in patients… read more here.
Keywords: bipolar depression; depression; adjunctive therapy; patients bipolar ... See more keywords
Efficacy of a multispecies probiotic as adjunctive therapy in generalized anxiety disorder: a double blind, randomized, placebo-controlled trial
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DOI: 10.1080/1028415x.2019.1598669
Abstract: ABSTRACT Objectives: Studies have shown that probiotics may decrease anxiety symptoms, but to our knowledge so far no trial has investigated the effects of probiotics in generalized anxiety disorder (GAD). The aim of the present… read more here.
Keywords: adjunctive therapy; anxiety disorder; generalized anxiety; anxiety ... See more keywords
Everolimus as adjunctive therapy for tuberous sclerosis complex-associated partial-onset seizures
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DOI: 10.1080/14737175.2019.1635457
Abstract: ABSTRACT Introduction: Tuberous sclerosis complex (TSC) is a rare genetic disorder resulting in benign tumors in various organs. It is caused by mutations in TSC1 or TSC2 genes causing hyperactivation of the mammalian target of… read more here.
Keywords: tuberous sclerosis; adjunctive therapy; sclerosis complex; tsc ... See more keywords
Adjunctive therapy to treat neonatal sepsis
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DOI: 10.1080/17512433.2020.1699790
Abstract: ABSTRACT Introduction: Neonatal sepsis (NS) is a very severe condition that causes significant morbidity and mortality. Areas covered: To overcome the limits of antibiotic therapy and improve NS outcomes, measures chosen among those theoretically able… read more here.
Keywords: sepsis; adjunctive therapy; neonatal sepsis; treat neonatal ... See more keywords
Randomized Controlled Study to Evaluate the Efficacy and Safety of Soticlestat as Adjunctive Therapy in Adults with Complex Regional Pain Syndrome.
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DOI: 10.1093/pm/pnac198
Abstract: OBJECTIVE The objective was to investigate the efficacy and safety of soticlestat as adjunctive therapy in participants with complex regional pain syndrome (CRPS). DESIGN A proof-of-concept phase 2a study, comprising a 15-week randomized, double-blind, placebo-controlled,… read more here.
Keywords: safety soticlestat; adjunctive therapy; pain; efficacy safety ... See more keywords
998: ESOPHAGOGASTRODUODENOSCOPY AS AN ADJUNCTIVE THERAPY IN DRUG OVERDOSE
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DOI: 10.1097/01.ccm.0000642928.10551.cb
Abstract: Introduction: Esophagogastroduodenoscopy (EGD) has been described as a necessary route of intestinal decontamination in the presence of a pharmacobezoar but may also have further utility in other overdose patients. We describe a life-threatening ingestion complicated… read more here.
Keywords: adjunctive therapy; therapy; drug overdose; 998 esophagogastroduodenoscopy ... See more keywords
Tetracyclines, a promise for neuropsychiatric disorders: from adjunctive therapy to the discovery of new targets for rational drug design in psychiatry
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DOI: 10.1097/fbp.0000000000000585
Abstract: Major mental disorders, such as schizophrenia, bipolar disorder, and major depressive disorder, represent the leading cause of disability worldwide. Nevertheless, the current pharmacotherapy has several limitations, and a large portion of patients do not respond… read more here.
Keywords: adjunctive therapy; targets rational; neuropsychiatric disorders; new targets ... See more keywords
Adjunctive therapy with statins reduces residual albuminuria/proteinuria and provides further renoprotection by downregulating the angiotensin II–AT1 pathway in hypertensive nephropathy
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DOI: 10.1097/hjh.0000000000001325
Abstract: Objectives: Blockade of the renin–angiotensin II (Ang II) system by AT1 blockers (ARBs) and angiotensin-converting enzyme inhibitors retards the progression of chronic kidney disease (CKD) by reducing albuminuria/proteinuria. However, many patients with CKD suffer from… read more here.
Keywords: residual albuminuria; adjunctive therapy; albuminuria proteinuria; at1 ... See more keywords