Matching‐adjusted indirect comparison of isatuximab plus carfilzomib and dexamethasone with daratumumab plus lenalidomide and dexamethasone in relapsed multiple myeloma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5584
Abstract: Lenalidomide‐based regimens are commonly used for early relapse in patients with relapsed and/or refractory multiple myeloma (RRMM) receiving at least one prior line of therapy. In the absence of head‐to‐head comparison, matching‐adjusted indirect comparison (MAIC)… read more here.
Keywords: matching adjusted; indirect comparison; comparison; adjusted indirect ... See more keywords
Assessing the Impact of a Matching Adjusted Indirect Comparison in a Bayesian Network Meta Analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Research synthesis methods"
DOI: 10.1002/jrsm.1372
Abstract: If IPD is available for some or all trials in an NMA, then incorporating this IPD into an NMA is routinely considered to be preferable. However, the situation often arises where a researcher has IPD… read more here.
Keywords: matching adjusted; network; adjusted indirect; indirect comparison ... See more keywords
Uncertain about uncertainty in matching‐adjusted indirect comparisons? A simulation study to compare methods for variance estimation
Sign Up to like & getrecommendations! Published in 2024 at "Research Synthesis Methods"
DOI: 10.1002/jrsm.1759
Abstract: In health technology assessment, matching‐adjusted indirect comparison (MAIC) is the most common method for pairwise comparisons that control for imbalances in baseline characteristics across trials. One of the primary challenges in MAIC is the need… read more here.
Keywords: matching adjusted; variance; variance estimation; uncertainty ... See more keywords
Quantitative bias analysis for unmeasured confounding in unanchored population-adjusted indirect comparisons
Sign Up to like & getrecommendations! Published in 2025 at "Research Synthesis Methods"
DOI: 10.1017/rsm.2025.13
Abstract: Unanchored population-adjusted indirect comparisons (PAICs) such as matching-adjusted indirect comparison (MAIC) and simulated treatment comparison (STC) attracted a significant attention in the health technology assessment field in recent years. These methods allow for indirect comparisons… read more here.
Keywords: indirect comparisons; quantitative bias; unanchored population; analysis ... See more keywords
OP49 Are Propensity-Score-Based Adjusted Indirect Comparisons Feasible For All European Joint Clinical Assessments Based On Non-Randomized Data?
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462324001119
Abstract: Introduction Involving the public is essential to building trust in health technology assessment (HTA) organizations. The National Institute for Health and Care Excellence (NICE) runs a deliberative public engagement program, NICE Listens. It was used… read more here.
Keywords: propensity score; op49 propensity; based adjusted; adjusted indirect ... See more keywords
PD39 First Approach For Assessing Statistical Significance In Industry Funded Matching-Adjusted Indirect Comparison Studies: A Scoping Review
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462324003027
Abstract: Introduction When indirectly compared trials are too heterogeneous to provide a reliable estimate, matching-adjusted indirect comparison (MAIC) studies can be employed. This technique is commonly used for oncology treatments. MAIC is an indirect comparison that… read more here.
Keywords: oncology; matching adjusted; industry; adjusted indirect ... See more keywords
Comparing the efficacy and safety of safinamide with rasagiline in China Parkinson’s disease patients with a matching adjusted indirect comparison
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-94960-9
Abstract: Safinamide and rasagiline are adjuncts to levodopa for the motor fluctuations of Parkinson’s Disease (PD). However, there remains a scarcity of head-to-head studies that directly compare safinamide and rasagiline. This study compared safinamide and rasagiline… read more here.
Keywords: matching adjusted; efficacy; safinamide rasagiline; adjusted indirect ... See more keywords
Matching-adjusted indirect comparison of enzalutamide versus darolutamide doublet in mHSPC
Sign Up to like & getrecommendations! Published in 2025 at "Future Oncology"
DOI: 10.1080/14796694.2025.2526324
Abstract: ABSTRACT Aims To compare the efficacy of enzalutamide + androgen-deprivation therapy (ADT) versus darolutamide + ADT for treatment of patients with metastatic hormone-sensitive prostate cancer (mHSPC) using a matching-adjusted indirect comparison (MAIC). Patients and methods Individual patient data from… read more here.
Keywords: matching adjusted; indirect comparison; darolutamide adt; adjusted indirect ... See more keywords
#368 Matching-Adjusted Indirect Comparisons of eGFR slopes in the PROTECT study with UK RaDaR IgA nephropathy population and the control arm of NefIgArd
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae069.426
Abstract: Immunoglobulin A nephropathy (IgAN) is a rare kidney disorder characterized by deposition of IgA in the glomeruli leading to an increased risk of kidney failure. The PROTECT clinical trial in IgAN was designed to determine… read more here.
Keywords: indirect comparisons; matching adjusted; clinical trial; trial ... See more keywords
Adjusted indirect comparisons to assess bioequivalence between generic clopidogrel products in Serbia
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13997
Abstract: Generic products can be regarded as therapeutically equivalent and switchable with the reference product. However, switchability between generics is unknown, as direct comparisons between generics are not performed. The aim of this study was to… read more here.
Keywords: generic clopidogrel; indirect comparisons; bioequivalence generic; clopidogrel products ... See more keywords
The Importance of Clinical Context and Consistency in Methodology When Using Matching-Adjusted Indirect Comparisons (MAICs) to Compare Outcomes
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s464226
Abstract: Abstract Hemophilia A is rare, which makes large, randomized, controlled, statistically driven, head-to-head comparison trials difficult. Matching-adjusted indirect comparisons (MAICs) are validated statistical tools designed to help make the results of non-comparative trials more comparable.… read more here.
Keywords: indirect comparisons; methodology; matching adjusted; comparisons maics ... See more keywords