Articles with "adjuvant" as a keyword



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Protective effect of Ganoderic acid A on adjuvant-induced arthritis.

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Published in 2020 at "Immunology letters"

DOI: 10.1016/j.imlet.2020.06.010

Abstract: The purpose of the experiment was to study the effect of Ganoderic acid A (GAA) on adjuvant-induced arthritis in rats. In this study, the rat model of collagen-induced rheumatoid arthritis (CIA) was established with type… read more here.

Keywords: ganoderic acid; pathology; effect; effect ganoderic ... See more keywords
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Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03.

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Published in 2017 at "Journal of virological methods"

DOI: 10.1016/j.jviromet.2016.12.014

Abstract: There is an urgent need for Ebola virus (EBOV) proteins, EBOV-specific antibodies and recombinant antigens to be used in diagnostics and as potential vaccine candidates. Our objective was to produce and purify recombinant proteins for… read more here.

Keywords: ebola virus; ebov; ebov proteins; adjuvant system ... See more keywords
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Brominated Carbazole with Antibiotic Adjuvant Activity Displays Pleiotropic Effects in MRSA's Transcriptome.

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Published in 2022 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00168

Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health, as the US mortality rate outweighs those from HIV, tuberculosis, and viral hepatitis combined. In the wake of the COVID-19 pandemic, antibiotic-resistant bacterial infections… read more here.

Keywords: adjuvant activity; adjuvant; brominated carbazole; antibiotic adjuvant ... See more keywords
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Melanoma: Neo/adjuvant BRAF/MEKi improves outcomes

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Published in 2018 at "Nature Reviews Clinical Oncology"

DOI: 10.1038/nrclinonc.2018.23

Abstract: Patients with stage III melanoma typically undergo surgery, followed by consideration for adjuvant therapy; however, only 30–50% of these patients are likely to survive >5 years after diagnosis. Now, the findings of a phase II… read more here.

Keywords: braf; group; improves outcomes; plus trametinib ... See more keywords
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Local delivery to malignant brain tumors: potential biomaterial-based therapeutic/adjuvant strategies.

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Published in 2021 at "Biomaterials science"

DOI: 10.1039/d1bm00896j

Abstract: Glioblastoma (GBM) is the most aggressive malignant brain tumor and is associated with a very poor prognosis. The standard treatment for newly diagnosed patients involves total tumor surgical resection (if possible), plus irradiation and adjuvant… read more here.

Keywords: malignant brain; delivery; local delivery; adjuvant ... See more keywords
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A comparative analysis of clinicopathological characteristics and disease-free survival (DFS) outcomes in breast cancer patients: Mammograpghy vs symptomatic diagnosis.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.e12018

Abstract: e12018Background: Our goal was to compare clinicopathological characteristics and DFS time among breast cancer patients diagnosed with mammography or symptoms. Methods: This was retrospective analysis of 828 patient files. Diagnosis was done with mammography or… read more here.

Keywords: analysis; adjuvant; breast cancer; clinicopathological characteristics ... See more keywords
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AddaVax Formulated with PolyI:C as a Potential Adjuvant of MDCK-based Influenza Vaccine Enhances Local, Cellular, and Antibody Protective Immune Response in Mice

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Published in 2021 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-021-02145-0

Abstract: Poor immune responses to inactivated influenza vaccine can be improved by effective and safe adjuvants to increase antibody titers and cellular protective response. In our study, AddaVax and PolyI:C combined adjuvant (AP adjuvant) were used… read more here.

Keywords: influenza vaccine; response; antibody; mice ... See more keywords
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The use of 4-Hexylresorcinol as antibiotic adjuvant

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0239147

Abstract: Ever decreasing efficiency of antibiotic treatment due to growing antibiotic resistance of pathogenic bacteria is a critical issue in clinical practice. The two generally accepted major approaches to this problem are the search for new… read more here.

Keywords: use hexylresorcinol; hexylresorcinol antibiotic; adjuvant; efficiency ... See more keywords
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Polymeric Approach to Adjuvant System in Antibody Production against Leishmaniasis Based on Hybridoma Technology

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Published in 2022 at "Iranian Journal of Parasitology"

DOI: 10.18502/ijpa.v17i4.11278

Abstract: Background: Leishmaniasis is a zoonotic disease, which is one of the serious public health problems in the world. Nowadays, antibody production using hybridoma technology may be a correct approach in terms of sensitivity in the… read more here.

Keywords: antibody production; hybridoma technology; adjuvant; antibody ... See more keywords
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Adjuvant combined therapy with trastuzumab in patients with HER2-positive breast cancer and cardiac alterations: implications for optimal cardio-oncology care.

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Published in 2022 at "Polish archives of internal medicine"

DOI: 10.20452/pamw.16204

Abstract: INTRODUCTION Recently, the prognosis of patients with HER2-positive breast cancer (BC) has improved significantly owing to the use of combined treatment modalities. However, systemic treatment is associated with increased risk of cardiotoxicity. OBJECTIVES We aimed… read more here.

Keywords: oncology; therapy; cardiac alterations; patients her2 ... See more keywords
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Lipidation Approaches Potentiate Adjuvant-Pulsed Immune Surveillance: A Design Rationale for Cancer Nanovaccine

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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2020.00787

Abstract: Adjuvant-pulsed peptide vaccines hold great promise for the prevention and treatment of different diseases including cancer. However, it has been difficult to maximize vaccine efficacy due to numerous obstacles including the unfavorable tolerability profile of… read more here.

Keywords: lipidation approaches; lipidation; adjuvant pulsed; approaches potentiate ... See more keywords