Association of Tumor-Associated Collagen Signature With Prognosis and Adjuvant Chemotherapy Benefits in Patients With Gastric Cancer
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DOI: 10.1001/jamanetworkopen.2021.36388
Abstract: Key Points Question Can the accuracy of prognosis prediction be improved using a tumor-associated collagen signature of gastric cancer (TACSGC) to detect patients who are likely to benefit from adjuvant chemotherapy for GC? Findings In… read more here.
Keywords: prognosis; adjuvant chemotherapy; collagen signature; tumor associated ... See more keywords
Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment.
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DOI: 10.1001/jamaoncol.2020.3537
Abstract: Importance The benefit of adjuvant chemotherapy after resection of pancreatic cancer following neoadjuvant combination treatment with folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) is unclear. Objective To assess the association of adjuvant chemotherapy with overall… read more here.
Keywords: chemotherapy; adjuvant chemotherapy; treatment; pancreatic cancer ... See more keywords
Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216).
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DOI: 10.1001/jamaoncol.2022.0039
Abstract: Importance Standard treatment for resectable non-small cell lung cancer (NSCLC) includes anatomic resection with adequate lymph node dissection and adjuvant chemotherapy for appropriate patients. Historically, many patients with early-stage NSCLC have not received such treatment,… read more here.
Keywords: early stage; adjuvant chemotherapy; chemotherapy; study ... See more keywords
Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy.
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DOI: 10.1001/jamaoncol.2022.5808
Abstract: Importance The total number of patients with pancreatic ductal adenocarcinoma (PDAC) who receive neoadjuvant chemotherapy (NAC) is increasing. However, the added role of adjuvant chemotherapy (AC) in these patients remains unknown. Objective To evaluate the… read more here.
Keywords: neoadjuvant chemotherapy; group; chemotherapy patients; adjuvant chemotherapy ... See more keywords
Association of Clinical Complications of Chemotherapy and Patient-Reported Outcomes After Immediate Breast Reconstruction.
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DOI: 10.1001/jamasurg.2021.2239
Abstract: Importance Women undergoing immediate breast reconstruction often require chemotherapy. The effects of chemotherapy on reconstruction are not well described. Objective To evaluate the association of neoadjuvant and adjuvant chemotherapy with complications and patient-reported outcomes (PROs)… read more here.
Keywords: reconstruction; chemotherapy; adjuvant chemotherapy; breast reconstruction ... See more keywords
Prospective analysis of different combined regimens of stereotactic body radiation therapy and chemotherapy for locally advanced pancreatic cancer
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DOI: 10.1002/cam4.1553
Abstract: To identify impacts of different combined regimens of stereotactic body radiation therapy (SBRT) and chemotherapy on survival of patients with locally advanced pancreatic cancer (LAPC) and factors correlated with determinations of different combinations. Four hundred… read more here.
Keywords: chemotherapy; adjuvant chemotherapy; different combined; months months ... See more keywords
Adjuvant chemotherapy versus chemoradiation in high‐risk pancreatic adenocarcinoma: A propensity score‐matched analysis
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DOI: 10.1002/cam4.2491
Abstract: The American Society of Clinical Oncology guidelines recommend adjuvant chemoradiation (ACR) for margin‐positive (R1) and/or node‐positive (N+) pancreatic cancers. Our goal was to investigate if there is evidence of superiority of adjuvant chemoradiation (ACR) over… read more here.
Keywords: adjuvant chemotherapy; versus chemoradiation; chemotherapy versus; chemoradiation high ... See more keywords
Impact of adjuvant chemotherapy on outcomes in appendiceal cancer
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DOI: 10.1002/cam4.3009
Abstract: The impact of using adjuvant chemotherapy following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with appendiceal adenocarcinoma is not known. The aim of this study was to assess the impact of adjuvant… read more here.
Keywords: chemotherapy; chemotherapy outcomes; adjuvant chemotherapy; cancer ... See more keywords
Delayed initiation of adjuvant chemotherapy in older women with breast cancer
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DOI: 10.1002/cam4.3363
Abstract: Adjuvant chemotherapy benefits early‐stage breast cancer (BC) patients. Older women receive guideline‐adherent treatment less frequently and experience treatment delays more frequently. We evaluated factors associated with delaying adjuvant chemotherapy and the delays’ survival impact in… read more here.
Keywords: chemotherapy; adjuvant chemotherapy; breast cancer; delayed initiation ... See more keywords
Comparative survival analysis of platinum‐based adjuvant chemotherapy for early‐stage squamous cell carcinoma and adenocarcinoma of the lung
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DOI: 10.1002/cam4.4570
Abstract: Although cytotoxic platinum‐based adjuvant chemotherapy (pACT) has been recommended for patients with completely resected early‐stage (ES) non–small‐cell lung cancer (ES‐NSCLC), therapeutic regimens for NSCLC have evolved in the past two decades. The study was aimed… read more here.
Keywords: cell; based adjuvant; early stage; squamous cell ... See more keywords
Who could complete and benefit from the adjuvant chemotherapy regarding pancreatic ductal adenocarcinoma? A multivariate‐adjusted analysis at the pre‐adjuvant chemotherapy timing
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DOI: 10.1002/cam4.4698
Abstract: The pre‐adjuvant chemotherapy (PAC) status of postoperative pancreatic ductal adenocarcinoma (PDAC) patients has not been studied and elaborated well previously. read more here.
Keywords: pre adjuvant; ductal adenocarcinoma; adjuvant chemotherapy; pancreatic ductal ... See more keywords