Duration of adjuvant immunotherapy—biologic, clinical and economic considerations
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DOI: 10.1007/s12032-018-1218-0
Abstract: The financial impact of an extensive duration of adjuvant immunotherapy is severe. The clinical and biological rationale for this extensive duration is unclear. This study aims to understand the biologic and clinical rationale for the… read more here.
Keywords: treatment; adjuvant immunotherapy; duration; duration adjuvant ... See more keywords
Adjuvant immunotherapy in renal cell carcinoma: a systematic review and meta‐analysis
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DOI: 10.1111/bju.15981
Abstract: To synthesise available data regarding the disease‐free survival (DFS) benefit of adjuvant immune checkpoint inhibitors (ICIs) for patients with renal cell carcinoma (RCC) and evaluate the overall safety profile of ICIs in this setting. read more here.
Keywords: adjuvant immunotherapy; cell carcinoma; renal cell; immunotherapy renal ... See more keywords
Efficacy and toxicity of adjuvant radiotherapy in recurrent melanoma after adjuvant immunotherapy
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DOI: 10.1136/jitc-2022-006629
Abstract: Background In patients with stage III melanoma, despite surgical resection and adjuvant systemic therapy, locoregional recurrences still occur. The randomized, phase III Trans-Tasman Radiation Oncology Group (TROG) 02.01 trial demonstrated that adjuvant radiotherapy (RT) after… read more here.
Keywords: adjuvant immunotherapy; recurrence; adjuvant radiotherapy; melanoma ... See more keywords
Abstract 875: Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescent probe-guided surgery and PD-1 adjuvant immunotherapy
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DOI: 10.1158/1538-7445.am2017-875
Abstract: Purpose: An intraoperative technique to accurately identify microscopic tumor residuals could be applied to decrease the risk of positive surgical margins. Several lines of evidence support the expression and immunotherapeutic effect of PD-1 in breast… read more here.
Keywords: probe; guided surgery; adjuvant immunotherapy; tumor ... See more keywords
ASO Author Reflections: Important Factors for Adjuvant Immunotherapy Treatment Decisions for Stage II–IV Melanoma Patients and Their Clinicians
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DOI: 10.1245/s10434-019-08020-4
Abstract: The factors important to melanoma patients and clinicians making decisions about adjuvant immunotherapy are not clearly defined. For localized melanoma, surgical resection is standard of care. Recently, adjuvant systemic immunotherapy with anti-PD-1 antibodies has improved… read more here.
Keywords: immunotherapy; patients clinicians; adjuvant immunotherapy; aso author ... See more keywords
Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model
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DOI: 10.2147/ijn.s149235
Abstract: An intraoperative technique to accurately identify microscopic tumor residuals could decrease the risk of positive surgical margins. Several lines of evidence support the expression and immunotherapeutic effect of PD-1 in breast cancer. Here, we sought… read more here.
Keywords: fluorescence; guided surgery; adjuvant immunotherapy; tumor ... See more keywords
Immune Checkpoint Inhibitors and Other Immune Therapies in Breast Cancer: A New Paradigm for Prolonged Adjuvant Immunotherapy
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DOI: 10.3390/biomedicines10102511
Abstract: Background: Breast cancer is the most common form of cancer in women worldwide. Advances in the early diagnosis and treatment of cancer in the last decade have progressively decreased the cancer mortality rate, and in… read more here.
Keywords: prolonged adjuvant; adjuvant immunotherapy; checkpoint inhibitors; immune checkpoint ... See more keywords
Disease Recurrence during Adjuvant Immune Checkpoint Inhibitor Treatment in Metastatic Melanoma: Clinical, Laboratory, and Radiological Characteristics in Patients from a Single Tertiary Referral Center
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DOI: 10.3390/ijms231810723
Abstract: Despite the dramatic improvements in recurrence-free survival in patients with metastatic melanoma treated with immune checkpoint inhibitors (ICI), a number of patients develop metastases during adjuvant therapy. It is not currently possible to predict which… read more here.
Keywords: adjuvant immunotherapy; recurrence; disease recurrence; metastatic melanoma ... See more keywords