Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men: the SABPA study
Sign Up to like & getrecommendations! Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2483-5
Abstract: The relationship of both asymmetric (ADMA) and symmetric (SDMA) dimethylarginine with carotid wall thickness is inconclusive especially among black populations. We aimed to compare carotid intima media thickness (cIMT) and dimethylarginine levels in 75 black… read more here.
Keywords: percentage change; dimethylarginine; black men; adma ... See more keywords
Effect of statin on arginine metabolites in treated HIV-infection.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.09.030
Abstract: BACKGROUND AND AIMS Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide and an independent risk factor for cardiovascular disease. We examined the effect of statin on ADMA in HIV + patients on stable ART, and whether… read more here.
Keywords: effect statin; arginine metabolites; hiv; effect ... See more keywords
Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2017.05.007
Abstract: AIM Asymmetric dimethylarginine (ADMA) is involved in the regulation of nitric oxide synthesis and in the maintenance of vascular tone and structure. But the role and status of ADMA in diabetes induced kidney injury is… read more here.
Keywords: adma; diabetic nephropathy; role; injury ... See more keywords
Impact of arsenic exposure on clinical biomarkers indicative of cardiovascular disease risk in Mexican women.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.11.088
Abstract: An appropriate and precise identification of high-risk individuals to develop cardiovascular diseases (CVD) is of high importance to reduce these kinds of diseases, a major health concern worldwide. Therefore, the aim of this research was… read more here.
Keywords: risk; mexican women; cvd biomarkers; fabp4 ... See more keywords
Asymmetric dimethylarginine (ADMA), a marker of endothelial dysfunction levels in metabolic syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.488
Abstract: The metabolic syndrome is an important health problem affecting approximately 20–30% of the adult population in many countries. Metabolic syndrome (MS) is a life-threatening syndrome in which the presence of systemic disorders such as obesity,… read more here.
Keywords: disease; adma marker; adma; metabolic syndrome ... See more keywords
DDAH-1, via regulation of ADMA levels, protects against ischemia-induced blood-brain barrier leakage
Sign Up to like & getrecommendations! Published in 2021 at "Laboratory Investigation"
DOI: 10.1038/s41374-021-00541-5
Abstract: Dimethylarginine dimethylamino hydrolase-1 (DDAH-1) is an important regulator of nitric oxide (NO) metabolism that has been implicated in the pathogenesis of cardiovascular diseases. Nevertheless, its role in cerebral ischemia still needs to be elucidated. Herein,… read more here.
Keywords: blood brain; adma; ischemia; brain barrier ... See more keywords
Alcohol Drinks Induce Acute Lowering in Circulating l-Arginine in Obese and Type 2 Diabetic Subjects.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal food"
DOI: 10.1089/jmf.2021.0045
Abstract: Since low serum l-arginine (Arg) and high asymmetric dimethylarginine (ADMA) can predict microvascular complications in type 2 diabetes mellitus (T2DM), we tested whether Arg and ADMA are affected by diet and physical activity in overweight/obese… read more here.
Keywords: lifestyle modification; arg adma; adma; drinks induce ... See more keywords
Positive Effects of Melatonin on Renal Nitric Oxide-Asymmetric Dimethylarginine Metabolism in Fructose-Fed Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2020.0084
Abstract: Background: The incidence of metabolic syndrome is increasing worldwide and this is mainly attributed to high carbohydrate intake, especially of fructose, and sedentary lifestyles. Nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS)… read more here.
Keywords: group; adma; nitric oxide; asymmetric dimethylarginine ... See more keywords
Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.ade5584
Abstract: Osteoarthritis (OA) is a degenerative disease with a series of metabolic changes accompanied by many altered enzymes. Here, we report that the down-regulated dimethylarginine dimethylaminohydrolase-1 (DDAH1) is accompanied by increased asymmetric dimethylarginine (ADMA) in degenerated… read more here.
Keywords: sox9; asymmetric dimethylarginine; dimethylarginine adma; metabolite asymmetric ... See more keywords
S141 A novel dimethylarginine dimethylaminohydrolase 1 (DDAH1) genetic variant associated with lower asymmetric dimethylarginine (ADMA) levels predicts accelerated lung function decline and mortality in idiopathic pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.147
Abstract: Background Increased nitric oxide (NO) and its generating enzyme, inducible nitric oxide synthase (iNOS), are observed in experimental models of idiopathic pulmonary fibrosis (IPF). Asymmetric dimethylarginine (ADMA) competitively inhibits iNOS and is hydrolysed by dimethylarginine… read more here.
Keywords: dimethylarginine; fibrosis; ddah1; decline ... See more keywords
DDAH1/ADMA Regulates Adiponectin Resistance in Cerebral Ischemia via the ROS/FOXO1/APR1 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2350857
Abstract: Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA). This study is aimed at exploring the effect of adiponectin resistance on ADMA-induced neuronal loss in ischemic stroke… read more here.
Keywords: cerebral ischemia; adiponectin resistance; adma; ddah1 ... See more keywords