Novel huperzine A based NMDA antagonists: insights from molecular docking, ADME/T and molecular dynamics simulation studies
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra00722f
Abstract: The in silico study explores the structural behavior and binding affinities of 40 novel analogues of huperzine A. Novel NMDA receptor antagonists have been virtually identified by molecular docking, ADME/T and molecular dynamics simulation studies. read more here.
Keywords: docking adme; adme molecular; simulation studies; molecular dynamics ... See more keywords
Synthesis, ADME, Molecular Docking, and Biological Evaluation of New 2-Aminobenzothiazloes
Sign Up to like & getrecommendations! Published in 2023 at "Current Bioactive Compounds"
DOI: 10.2174/1573407219666230512121913
Abstract: In recent years, 2-aminobenzothiazoles were reported as antibacterial, antihelmintic, antitumor, antimalarial, antiviral, analgesic and anti-inflammatory agents. The study aimed to explore new potential 2-aminobenzothiazoles as antibacterial and anthelmintic agents. A favorable two-step method was used… read more here.
Keywords: molecular docking; biological evaluation; synthesis adme; adme molecular ... See more keywords