Edaravone Administered Orally and Via Nasogastric Tube in Healthy Adults: A Comparative Bioavailability Phase 1 Study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1175
Abstract: Intravenous edaravone is used to treat patients with amyotrophic lateral sclerosis. This randomized, open‐label, two‐way crossover, single‐dose phase 1 study compared the relative bioavailability of a newly developed edaravone oral suspension when administered orally and… read more here.
Keywords: orally via; bioavailability; phase study; tube ... See more keywords
Pharmacokinetics and pharmacodynamics of the injectable formulation of methadone hydrochloride and methadone in lipid nanocarriers administered orally to horses
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Veterinary Pharmacology and Therapeutics"
DOI: 10.1111/jvp.12393
Abstract: We investigated the thermal, electrical and mechanical antinociceptive and physiological effects (heart rate, respiratory rate, arterial blood pressure, head height and abdominal auscultation score), and pharmacokinetics, of 0.5 mg/kg of the injectable formulation (ORAL) or nanoparticulated… read more here.
Keywords: administered orally; injectable formulation; methadone; orally horses ... See more keywords