Virologic Efficacy of Casirivimab and Imdevimab COVID-19 Antibody Combination in Outpatients With SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.25411
Abstract: Key Points Question Can casirivimab and imdevimab effectively reduce the viral load of SARS-CoV-2 with lower doses and a subcutaneous route of administration? Findings In this phase 2 randomized clinical trial of outpatients with SARS-CoV-2,… read more here.
Keywords: administration; outpatients sars; casirivimab imdevimab; imdevimab ... See more keywords
Association of Intravenous Potassium and Magnesium Administration With Spontaneous Conversion of Atrial Fibrillation and Atrial Flutter in the Emergency Department
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.37234
Abstract: Key Points Question Is the administration of potassium and magnesium associated with the probability of spontaneous conversion of nonpermanent atrial fibrillation and atrial flutter in the emergency department? Findings In this cohort study that included… read more here.
Keywords: atrial flutter; potassium magnesium; atrial fibrillation; administration ... See more keywords
Trends in COVID-19 Vaccine Administration and Effectiveness Through October 2021
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.5018
Abstract: This cohort study reports statewide trends in vaccine administration and vaccine effectiveness in Minnesota. read more here.
Keywords: administration; vaccine administration; effectiveness october; trends covid ... See more keywords
Association of Radiation Therapy With Risk of Adverse Events in Patients Receiving Immunotherapy: A Pooled Analysis of Trials in the US Food and Drug Administration Database.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2021.6439
Abstract: Importance Immune checkpoint inhibitors (ICIs) and radiation therapy (RT) are widely used to treat various cancers, but little data are available to guide clinicians on ICI use sequentially with RT. Objective To assess whether there… read more here.
Keywords: within days; administration; therapy; risk ... See more keywords
Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals With Survival and Morbidity Among Very Preterm Infants: Results From the EPICE Cohort
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.0602
Abstract: Importance Administration-to-birth intervals of antenatal corticosteroids (ANS) vary. The significance of this variation is unclear. Specifically, to our knowledge, the shortest effective administration-to-birth interval is unknown. Objective To explore the associations between ANS administration-to-birth interval… read more here.
Keywords: administration; birth intervals; birth; mortality ... See more keywords
Association Between Early Caffeine Citrate Administration and Risk of Acute Kidney Injury in Preterm Neonates: Results From the AWAKEN Study
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2018.0322
Abstract: Importance Acute kidney injury (AKI) occurs commonly in preterm neonates and is associated with increased morbidity and mortality. Objectives To examine the association between caffeine citrate administration and AKI in preterm neonates in the first… read more here.
Keywords: administration; kidney injury; caffeine; acute kidney ... See more keywords
Evaluation of Military Use of Tranexamic Acid and Associated Thromboembolic Events
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2017.3821
Abstract: Importance Since publication of the CRASH-2 and MATTERs studies, the US military has included tranexamic acid (TXA) in clinical practice guidelines. While TXA was shown to decrease mortality in trauma patients requiring massive transfusion, improper… read more here.
Keywords: administration; txa administration; tranexamic acid; venous thromboembolism ... See more keywords
Maternal probiotic supplementation for prevention of morbidity and mortality in preterm infants
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd012519
Abstract: BACKGROUND Inflammation may contribute to preterm birth and to morbidity of preterm infants. Preterm infants are at risk for alterations in the normal protective microbiome. Oral probiotics administered directly to preterm infants have been shown… read more here.
Keywords: administration; preterm birth; birth; preterm infants ... See more keywords
Acute Oral Administration of Single‐Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701313
Abstract: With the increasing production and widespread potential applications of single-walled carbon nanotubes (SWCNTs), the possible impacts of oral administration of SWCNTs on gastrointestinal tract at currently occupational exposure limits and potential biomedical applications should be… read more here.
Keywords: administration; walled carbon; single walled; gut microbiota ... See more keywords
Red Blood Cell Anchoring Enables Targeted Transduction and Re‐Administration of AAV‐Mediated Gene Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201293
Abstract: Adeno‐associated virus (AAV)‐mediated gene therapy is a promising therapeutic modality for curing many diseases including monogenic diseases. However, limited tissue‐targeting and restricted re‐administration due to the vector immunogenicity largely restrict its therapeutic potential. Here, using… read more here.
Keywords: aav mediated; administration; gene therapy; transduction ... See more keywords
Biocompatible mucoadhesive nanoparticles for brain targeting of ropinirole hydrochloride: Formulations, radiolabeling and biodistribution.
Sign Up to like & getrecommendations! Published in 2022 at "Biopolymers"
DOI: 10.1002/bip.23489
Abstract: Two nanoformulations with mucoadhesive properties and brain-targeting mechanisms were designed to deliver the anti-Parkinson's drug, ropinirole hydrochloride (RH). In the first formulation, RH and the amphiphilic block copolymer methoxy poly(ethylene glycol)-b-poly(caprolactone) were assembled in a… read more here.
Keywords: administration; brain targeting; biodistribution; ropinirole hydrochloride ... See more keywords