Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis
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DOI: 10.3389/fphar.2022.996635
Abstract: Transdifferentiation of keratocytes into fibroblasts or further into myofibroblasts, which produced denser and more disorganized extracellular matrix, is the major cause of corneal fibrosis and scarring, leading to corneal blindness. TGF-β1 is the critical cytokine… read more here.
Keywords: hypoxia inducible; administration acriflavine; fibrosis; corneal fibrosis ... See more keywords